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  • Cellular architecture of normal human skin imaged by whole mount tissue microscopy. Human skin has a rich network of white blood cells (specifically dendritic cells, T cells and macrophages) which form sheaths around blood vessels. In this image, blood vessels (string-like structures stained for CD31; green), lymphatic vessels (ribbon-like structures stained for LYVE-1; blue) and T cells (stained for CD3; red) can be seen. T cells are only found around dermal blood vessels. Macrophages (stained for LYVE-1; blue) are also present. This normal cellular architecture is grossly disrupted in diseased skin (see related images). X10 magnification. Scale bar (white) represents 200 micrometres.
  • Cellular architecture of normal human skin imaged by whole mount tissue microscopy. Human skin has a rich network of white blood cells (specifically dendritic cells, T cells and macrophages) which form sheaths around blood vessels. In this image, T cells (stained for CD3; red) dendritic cells (stained for MHC class II; green) and macrophages (stained for LYVE-1; blue with some cells showing a tinge of green) can be seen. Cell nuclei have been stained with DAPI (grey). This normal cellular architecture is grossly disrupted in diseased skin (see related images). X20 magnification. Scale bar (white) represents 100 micrometres.
  • Cellular architecture of normal human skin imaged by whole mount tissue microscopy. Human skin has a rich network of white blood cells (specifically dendritic cells, T cells and macrophages) which form sheaths around blood vessels. This image was taken greater than 150 micrometres beneath the junction that joins the dermal and epidermal layers of the skin (dermo-epidermal junction). At this level, dendritic cells (stained for CD11c; green) and macrophages (stained for LYVE-1; blue) form clusters around blood vessels (stained for CD31; red). This normal cellular architecture is grossly disrupted in diseased skin (see related images). Scale bar (white) represents 100 micrometres.
  • Cellular architecture of human skin lymphoma imaged by whole mount tissue microscopy. Normal human skin has a rich network of white blood cells (specifically dendritic cells, T cells and macrophages) which form sheaths around blood vessels. In diseased skin, such as in skin lymphoma as seen here, this normal architecture becomes distorted. In this image, lots of T cells (stained for CD3; red), dendritic cells (stained for CD11c; green) and macrophages (stained for LYVE-1; blue) have infiltrated the skin. X20 magnification. Scale bar (white) represents 100 micrometres.
  • Blood vessel in a melanoma, SEM
  • Cell in laser beam, flow cytometry, illustration
  • Blood vessel in a melanoma, SEM
  • Fungal elements engulfed by neutrophils
  • Fungal elements engulfed by neutrophils- col
  • A.E. Wright, Handbook of the technique of
  • Fungal hyphae in the eye - TEM
  • Fungal infection after corneal graft
  • Tuberculous meningitis
  • Fungal hyphae in the eye - TEM
  • J. Cropper, A phenomenal abundance of parasi
  • Longitudinal section of a small blood vessel