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229 results
  • Human chromosomes, histones and kinetochores
  • Human chromosomes and spindle at anaphase
  • Human chromosomes and spindle at anaphase
  • Human chromosomes and spindle at metaphase
  • Human chromosomes and spindle at metaphase
  • Human chromosomes in a cancer cell
  • Mitotic cell showing chromosomes - TEM
  • Human chromosomes at three stages of mitosis
  • Turner's syndrome karyotype 45,XO. This female lacks the second X chromosome present in the normal karyotype. Symptoms include short stature, neck wbbing, elbow deformity, widely spaced nipples with shield chest, primary amenorrhea, sexual infantilism and sterility. The ovaries are reduced to fibrous streaks. Also known as XO syndrome or ovarian short-stature syndrome.
  • Human chromosomes in metaphase. The chromosomes are all aligned and at this stage they are attached to the spindle (not visible in this image).
  • Illustration of the human chromosomes sequenced in the UK
  • Human chromosomes in late anaphase. At this stage the chromosomes have started to separate from each other and move towards opposite poles of the cell.
  • Human chromosomes in early anaphase. At this stage the chromosomes have started to separate from each other and move towardds opposite poles of the cell.
  • Nucleus in prometaphase. The chromosomes are stained green. The chromatin has condensed but there is not yet complete attachment of the chromosomes to the spindle (not visible in the image).
  • Human chromosomes in early anaphase. At this stage the chromosomes have started to separate from each other and move towards opposite poles of the cell. The chromatin appears grey and the kinetochores are pink.
  • Human chromosomes in metaphase. The chromatin is stained red and the "glue" that holds the two chromatids together is highlighted in yellow. This glue is a proteinaceous complex called cohesin. Once all the chromosomes are attached to the spindle, the cohesin complex breaks down, allowing the two chromatids to separate and move to opposite poles of the cell.
  • Human karyotype showing translocation between chromosomes 14 and 21, t(14;21). This is a balanced translocation - the cell retains a normal complement of genetic information.
  • HeLa cell in prometaphase. The chromatin is stained red and the microtubules forming the spindle stained green. The chromatin has condensed but there is not yet complete attachment of the chromosomes to the spindle.
  • Genetics frame of reference - the size of various genetic components, including DNA, a base pair, various sizes of deletions, chromosomes and genes are listed and compared with more familiar objects such as the Solar System, planets, cities, hospitals, wards, and so on.
  • Balanced translocation 45,XY,t(13;14)
  • Fragile X pedigree + rflp autoradiograph
  • Down syndrome human karyotype 47,XY,+21
  • Unbalanced translocation 46,XY,t(14;21)
  • Unbalanced translocation 46,XY,t(13;14)
  • Unbalanced translocation 46,XY,t(21;21)
  • Fragile X metaphase spread
  • Balanced translocation 45,XY,t(14;21)
  • Balanced translocation 46,XY,t(4;10)
  • Acute myelomonocytic leukaemia +eosinophilia
  • DNA sequencing using cosmids for c'some 9