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  • Aspirin crystals. Aspirin was originally extracted from willow bark but is actually produced in all plants as a defence mechanism in response to damage or attack. Much higher levels are therefore found in less than perfect fruit and vegetables. Aspirin is used to treat pain, reduce fever and to prevent heart disease and cancer. Some people think it should be reclassified as a vitamin.
  • Cistus incanus ssp creticus Juss. Cistaceae. Rock Rose. Distribution: Crete. Interesting symbiosis with fungus called Tuber melanosporum which increases nutrient absorption for the plant and inhibits growth of other plants in the vicinity. It is a source of the resin ‘labdanum’ (a.k.a. ‘ladanum’) used in perfumes (similar smell to ambergris), as is Cistus ladanifer. It has no medical uses now, and such use was dwindling even in the 18th century. In the 16th century (Henry Lyte’s 1575 translation of Rembert Dodoen’s Cruydeboeck of 1554) its uses were described (directly copied from Dioscorides’ Materia Medica (70AD)) as: ‘Ladanum dronketh with olde wine, stoppeth the laske [periods], and provoketh urine. It is very good against the hardness of the matrix or mother [uterus] layde to in the manner of a pessarie, and it draweth down the secondes or afterbirth, when it is layde upon quicke coles [hot coals], and the fumigation or parfume thereof be received up into the body of women. // The same applied to the head with Myrrhe and oyle of Myrrhe, cureth the scurffe, called Alopecia, and keepeth the heare [hair] from falling of [sic], but whereas it is already fallen away, it will not cause the heare to growe agayne. // ...' and goes on in this vein about its uses for pain in the ears, and removing sores and scars and other things. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Catharanthus roseus (L.)G.Don Apocynaceae. Madagascar Periwinkle Distribution: Madagascar. It is the source of vincristine and vinblastine, which impair cell multiplication by interfering with microtubule assembly, causing metaphase arrest and are effective medications for leukaemias, lymphomas and some solid tumours. The mortality from childhood leukaemia fell from 100% to 30% once it was introduced - not a drug that could ethically be tested by double-blind trials. These chemicals were initially discovered by investigators in 1958 who were looking for cures for diabetes so tested this plant which was being used in the West Indies to reduce blood sugar levels. There are 70 different alkaloids present in this plant, and some - catharanthine, leurosine sulphate, lochnerine, tetrahydroalstonine, vindoline and vindolinine - lower blood sugar levels. However, the toxicity of this plant is such that this is not a plant to try at home for diabetic management. The vincristine content of the plant is 0.0003%, so two kilograms of leaf are required to produce sufficient vincristine for a single course of treatment for a child (6gm). Fortunately it is a vigorous weed and easy to grow in the tropics. Artificial synthesis has now been achieved. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Galega officinalis L. Fabaceae. Goat's Rue. Distribution: Central and Southern Europe, Asia Minor. Culpeper (1650) writes that it ‘... resists poison, kills worms, resists the falling sickness [epilepsy], resisteth the pestilence.’ Galega officinalis contains guanidine which reduces blood sugar by decreasing insulin resistance and inhibiting hepatic gluconeogenesis.. Metformin and Phenformin are drugs for type II diabetes that rely on this group of chemicals, known as biguanidines. Its name gala, meaning milk plus ega meaning 'to bring on', refers to its alleged property of increasing milk yield, and has been used in France to increase milk yield in cows. officinalis refers to its use in the offices of the monks, and is a common specific name for medicinal plants before 1600 and adopted by Linnaeus (1753). The fresh plant tastes of pea pods. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Pulmonaria officinalis L. Boraginaceae Distribution: Europe. Pulmonaria or Lungwort are names for a lichen and a perennial plant in the Boraginaceae. This is the latter. Lyte (1578) has a woodcut of our plant and also calls it Sage of Jerusalem and says it is of 'no particular use in physicke, but is much used in meates and salads with eggs, as is also Cowslippes and Primroses, whereunto in temperature it is much alike.' He lists and describes the lichen separately. Culpeper (1650) said he found many sorts of lunguewort in perusing Authors ' Pulmonari, arborea and Symphytum maculosum [and the latter is our plant, the others the lichen] and that they 'helpe infirmities of the lungues, as hoarseness, coughs, wheezing, shortnesse of breath etc.' Coles (1657) who espouses the Doctrine of Signatures in a way unrivalled by any other English author, might have been expected to confirm the concept that the mottled leaves looked like the cut surface of a lung which indicates their purpose, but he only mentions the lungwort which is a lichen. However, Porta's beautiful book on the Doctrine, Phytognomica (1588), is clear that the plant called Pulmonaria with hairy leaves like a bugloss, spotted white with purple flowers, commonly called 'cynoglossa' [with a woodcut which could be Pulmonaria officinalis] indicate its use for ulcerated lungs, spitting blood, shortness of breath and asthma equally with the lichen with the same name. Lobel & Pena (1570) call it 'PULMONARIA, masculosa folia Borrago. floribus Primula veris, purpureis [PULMONARIA spotted, Borage-leaved, flowers like Primula veris - Cowslips - purple]' and say that women mix the leaves with a little broth and make it into an omelette for lung disorders and to strengthen the heart.. Lobel (1576) calls it Maculosa Pulmonaria and describes a white flowered form with a good woodcut. Gerard (1633) uses the same woodcut as Lobel and calls it Pulmonatia foliis Echii, Buglosse Cowslips with red flowers, and a woodcut of a narrow leaved plant as Pulmonaria masculosa, Spotted Cowslips of Jerusalem with red, blue and purple flowers and says 'the leaves are used among pot-herbes. The roots are aso thought to be good against the infirmities of ulcers of the lungs...'. Quincy (1718) writes: '... it has a glutinous juice ... and heals ulcers and erosions. It is commended in coughs and spitting of blood but is little used either in the Shop or Prescriptions'. Not used in modern medicine. It is in the family Boraginaceae whose species are often rich in pyrrolizidine alkaloids that cause liver toxicity and liver cancers, but levels in Pulmonaria officinalis may not be significant. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Pulmonaria rubra L. Boraginaceae A red-flowered species, mentioned in 16th and 17th herbals, but with the same properties as officinalis. Distribution: Europe. Pulmonaria or Lungwort are names for a lichen and a perennial plant in the Boraginaceae. This is the latter. Lyte (1578) has a woodcut of our plant and also calls it Sage of Jerusalem and says it is of 'no particular use in physicke, but is much used in meates and salads with eggs, as is also Cowslippes and Primroses, whereunto in temperature it is much alike.' He lists and describes the lichen separately. Culpeper (1650) said he found many sorts of lunguewort in perusing Authors 'Pulmonari, arborea and Symphytum maculosum [and the latter is our plant, the others the lichen] and that they 'helpe infirmities of the lungues, as hoarseness, coughs, wheezing, shortnesse of breath etc.' Coles (1657) who espouses the Doctrine of Signatures in a way unrivalled by any other English author, might have been expected to confirm the concept that the mottled leaves looked like the cut surface of a lung which indicates their purpose, but he only mentions the lungwort which is a lichen. However, Porta's beautiful book on the Doctrine, Phytognomica (1588), is clear that the plant called pulmonaria with hairy leaves like a bugloss, spotted white with purple flowers, commonly called 'cynoglossa' [with a woodcut which could be Pulmonaria officinalis] indicate its use for ulcerated lungs, spitting blood, shortness of breath and asthma equally with the lichen with the same name. Lobel & Pena (1570) call it 'PULMONARIA, masculosa folia Borrago. floribus Primula veris, purpureis[ PULMONARIA spotted, Borage-leaved, flowers like Primula veris - Cowslips - purple] and say that women mix the leaves with a little broth and make it into an omelette for lung disorders and to strengthen the heart. Lobel (1576) calls it Maculosa Pulmonaria and describes a white flowered form, with a good woodcut. Gerard (1633) uses the same woodcut as Lobel and calls it Pulmonatia foliis Echii, Buglosse Cowslips with red flowers, and a woodcut of a narrow leaved plant as Pulmonaria masculosa, Spotted Cowslips of Jerusalem with red, blue and purple flowers and says 'the leaves are used among pot-herbes. The roots are aso thought to be good against the infirmities of ulcers of the lungs...'. Quincy (1718) writes: '... it has a glutinous juice ... and heals ulcers and erosions. It is commended in coughs and spitting of blood but is little used either in the Shop or Prescriptions. Not used in modern medicine. It is in the family Boraginaceae whose species are often rich in pyrrolizidine alkaloids that cause liver toxicity and liver cancers, but levels in Pulmonaria officinalis may not be significant. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Lobelia tupa L Campanulaceae Tabaco del Diablo [Devil's tobacco]. Distribution: Central Chile. Dried leaves are smoked as a hallucinogen by the Mapuchu Indians of Chile. It was also used as a respiratory stimulant. The genus was named after Matthias de L’Obel or Lobel, (1538–1616), Flemish botanist and physician to James I of England, author of the great herbal Plantarum seu Stirpium Historia (1576). Lobeline, a chemical from the plant has nicotine like actions and for a while lobeline was used to help people withdraw from smoking, but was found to be ineffective. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Senna corymbosa (Lam.)H.S.Irwin&Barneby Caesalpinaceae. Argentine Senna. Distribution: Argentine (other species from Europe). This beautiful shrub that flowers from midsummer until the frosts of winter, is the source of one of the best known of all herbal medicines – Senokot (and senna pods and senna tea), introduced to European medicine (as Senna alexandrina from Egypt) by the Arabians. Every part of the plant contains anthraquinones which, if taken internally, act as a powerful laxative to treat constipation by stimulating the nerve cells of the large bowel. Gerard (1633) notes ‘it is a singular purging medicine’ with over a page on its uses. When used regularly the nerves to the large bowel may be destroyed, leaving a permanently dilated large bowel that never functions properly again. This is a plant which causes the condition it treats to become permanent. Additionally, with prolonged use, the lining of the bowel turns black, serum potassium levels may fall, resulting in cardiac irregularities and sometimes death. Coma, neuropathy and hepatitis have also been reported. It is advertised on television (the actor involved is seen to be depressed and bloated until she takes Senokot, after which she is happy - Hippocrates would have attributed this antidepressant effect to the plant's ability to purge her of the black melancholic humour present in her bowel motions). It is available without prescription or health warning against long-term use. What do you think? Lyte (1578) recommends it strongly for depression, but one might claim to be cured rather than take it again. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Senna corymbosa (Lam.)H.S.Irwin&Barneby Caesalpinaceae. Argentine Senna. Distribution: Argentine (other species from Europe). This beautiful shrub that flowers from midsummer until the frosts of winter, is the source of one of the best known of all herbal medicines – Senokot (and senna pods and senna tea), introduced to European medicine (as Senna alexandrina from Egypt) by the Arabians. Every part of the plant contains anthraquinones which, if taken internally, act as a powerful laxative to treat constipation by stimulating the nerve cells of the large bowel. Gerard (1633) notes ‘it is a singular purging medicine’ with over a page on its uses. When used regularly the nerves to the large bowel may be destroyed, leaving a permanently dilated large bowel that never functions properly again. This is a plant which causes the condition it treats to become permanent. Additionally, with prolonged use, the lining of the bowel turns black, serum potassium levels may fall, resulting in cardiac irregularities and sometimes death. Coma, neuropathy and hepatitis have also been reported. It is advertised on television (the actor involved is seen to be depressed and bloated until she takes Senokot, after which she is happy - Hippocrates would have attributed this antidepressant effect to the plant's ability to purge her of the black melancholic humour present in her bowel motions). It is available without prescription or health warning against long-term use. What do you think? Lyte (1578) recommends it strongly for depression, but one might claim to be cured rather than take it again. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Colchicum autumnale L., Colchicaceae. Autumn crocus, meadow saffron, naked ladies. Distribution: Europe. Extremely toxic, containing colchicine which is effective in small doses in treating gout. It inhibits mitosis so is of interest in cancer treatment. It is used to treat Familial Mediterranean fever. It induces polyploidy in plant protocorms for the production of tetraploid forms which have bigger flowers and seeds. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Camellia sasanqua Thunb. Theaceae. Christmas camellia. Camellia commemorates Georg Josef Kamel (1661-1706), Jesuit pharmacist from Moravia (Czech Republic) who worked in the Philippines and sent plants to John Ray in England (Oakeley, 2012) Evergreen shrub. Distribution: Japan and China. Leaves are used in Japan to make tea (normally made from C. sinensis) and the seeds to make the edible tea seed oil. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Hypericum olympicum L. Clusiaceae. Mount Olympus St John's wort. Deciduous perennial herb. Distribution Greece, Asia minor. This is not the plant used for mood disturbances in herbal medicine which is Hypericum perforatum. However, all the 370 species of Hypericum are called 'St John's Wort' so a potential for confusion exists. It shares some of the chemicals thought to be active in Hypericum perforatum. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Polypharmakos kai chymistēs: or, The English unparalell'd physitian and chyrurgian : shewing the true use of all manner of plants and minerals. In which is explained, the whole art and secresy of physick and chyrurgery. Wherein is contained, 1. The cure of any internal disease, which hath taken effect, and brought forth symptoms, ... 2. The making of diverse rare and excellent balsames, oyls, plaisters, and waters, with the effects thereof. 3. The making, and use of purges, vomits, drinks, and clisters, ... 4. The nature and temperarure [sic] of herbs, plants, and vegetables, ... 5. The way to extract the spirits and quintaessences of several sorts of herbs and minerals, and the rare operations they have. 6. The making of salt of wormwood, balm, or any other herb. 7. The cure of any wound, contusion, puncture, or ulcer in any part of the body. All which have been prescribed and practised by several learned doctors and chyrurgians. / By D. Border, practitioner in physick.
  • Polypharmakos kai chymistēs: or, The English unparalell'd physitian and chyrurgian : shewing the true use of all manner of plants and minerals. In which is explained, the whole art and secresy of physick and chyrurgery. Wherein is contained, 1. The cure of any internal disease, which hath taken effect, and brought forth symptoms, ... 2. The making of diverse rare and excellent balsames, oyls, plaisters, and waters, with the effects thereof. 3. The making, and use of purges, vomits, drinks, and clisters, ... 4. The nature and temperarure [sic] of herbs, plants, and vegetables, ... 5. The way to extract the spirits and quintaessences of several sorts of herbs and minerals, and the rare operations they have. 6. The making of salt of wormwood, balm, or any other herb. 7. The cure of any wound, contusion, puncture, or ulcer in any part of the body. All which have been prescribed and practised by several learned doctors and chyrurgians. / By D. Border, practitioner in physick.
  • Polypharmakos kai chymistēs: or, The English unparalell'd physitian and chyrurgian : shewing the true use of all manner of plants and minerals. In which is explained, the whole art and secresy of physick and chyrurgery. Wherein is contained, 1. The cure of any internal disease, which hath taken effect, and brought forth symptoms, ... 2. The making of diverse rare and excellent balsames, oyls, plaisters, and waters, with the effects thereof. 3. The making, and use of purges, vomits, drinks, and clisters, ... 4. The nature and temperarure [sic] of herbs, plants, and vegetables, ... 5. The way to extract the spirits and quintaessences of several sorts of herbs and minerals, and the rare operations they have. 6. The making of salt of wormwood, balm, or any other herb. 7. The cure of any wound, contusion, puncture, or ulcer in any part of the body. All which have been prescribed and practised by several learned doctors and chyrurgians. / By D. Border, practitioner in physick.
  • Polypharmakos kai chymistēs: or, The English unparalell'd physitian and chyrurgian : shewing the true use of all manner of plants and minerals. In which is explained, the whole art and secresy of physick and chyrurgery. Wherein is contained, 1. The cure of any internal disease, which hath taken effect, and brought forth symptoms, ... 2. The making of diverse rare and excellent balsames, oyls, plaisters, and waters, with the effects thereof. 3. The making, and use of purges, vomits, drinks, and clisters, ... 4. The nature and temperarure [sic] of herbs, plants, and vegetables, ... 5. The way to extract the spirits and quintaessences of several sorts of herbs and minerals, and the rare operations they have. 6. The making of salt of wormwood, balm, or any other herb. 7. The cure of any wound, contusion, puncture, or ulcer in any part of the body. All which have been prescribed and practised by several learned doctors and chyrurgians. / By D. Border, practitioner in physick.
  • Polypharmakos kai chymistēs: or, The English unparalell'd physitian and chyrurgian : shewing the true use of all manner of plants and minerals. In which is explained, the whole art and secresy of physick and chyrurgery. Wherein is contained, 1. The cure of any internal disease, which hath taken effect, and brought forth symptoms, ... 2. The making of diverse rare and excellent balsames, oyls, plaisters, and waters, with the effects thereof. 3. The making, and use of purges, vomits, drinks, and clisters, ... 4. The nature and temperarure [sic] of herbs, plants, and vegetables, ... 5. The way to extract the spirits and quintaessences of several sorts of herbs and minerals, and the rare operations they have. 6. The making of salt of wormwood, balm, or any other herb. 7. The cure of any wound, contusion, puncture, or ulcer in any part of the body. All which have been prescribed and practised by several learned doctors and chyrurgians. / By D. Border, practitioner in physick.
  • Polypharmakos kai chymistēs: or, The English unparalell'd physitian and chyrurgian : shewing the true use of all manner of plants and minerals. In which is explained, the whole art and secresy of physick and chyrurgery. Wherein is contained, 1. The cure of any internal disease, which hath taken effect, and brought forth symptoms, ... 2. The making of diverse rare and excellent balsames, oyls, plaisters, and waters, with the effects thereof. 3. The making, and use of purges, vomits, drinks, and clisters, ... 4. The nature and temperarure [sic] of herbs, plants, and vegetables, ... 5. The way to extract the spirits and quintaessences of several sorts of herbs and minerals, and the rare operations they have. 6. The making of salt of wormwood, balm, or any other herb. 7. The cure of any wound, contusion, puncture, or ulcer in any part of the body. All which have been prescribed and practised by several learned doctors and chyrurgians. / By D. Border, practitioner in physick.
  • Reseda lutea L. Resedaceae Wild Mignonette. Dyers Rocket. Herbaceous plant. Distribution: Eurasia and North Africa. This plant, and in particular R. luteola, is the source of 'weld' a yellow dye from luteolin a flavonoid in the sap. It is said to have been used since the first millennium BC, but curiously Dioscorides, Lyte, Gerard, Lobel, Fuchs, Coles, Quincy, Linnaeus (1782) either do not mention it or make it synonymous with Eruca, Rocket, and make no reference to it as a dye source. The name Resedo means 'I sit up' in Latin, which Stearn (1994) interprets as 'I heal' which makes its absence even more strange. It is noted as the dye source by Bentley (1861). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Magnolia stellata (Siebold & Zuch.) Maxim. Magnoliaceae. Star magnolia. Small flowering tree. Distribution: Japan. Named for the French botanist and physician, Pierre Magnol (1638-1715), Professor of Botany and Director of the Royal Botanic Gardens at Montpelier. Charles Plumier (1646-1704) named a tree on Martinique after him (Magnolia) and the name was continued by Linnaeus (1753). No medicinal use. This is a very ancient genus of flowering plants. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Joyfull newes out of the new-found worlde. Wherein are declared, the rare and singuler vertues of divers herbs, trees, plantes, oyles and stones, with their applications, as well to the use of phisicke, as of chirurgery ... Also the portrature of the said hearbs / ... Englished by John Frampton ... Newley corrected ... Whereunto are added three other bookes treating of the bezaar stone, the herb escuerconera, the properties of iron and steele, in medicine, and the benefit of snow.
  • Atropa belladonna L. Solanaceae. Deadly nightshade. Dwale. Morella, Solatrum, Hound's berries, Uva lupina, Cucubalus, Solanum lethale. Atropa derives from Atropos the oldest of the three Fates of Greek mythology who cut the thread of Life (her sisters Clotho and Lachesis spun and measured the thread, respectively). belladonna, literally, means 'beautiful lady' and was the Italian name for it. Folklore has it that Italian ladies put drops from the plant or the fruits in their eyes to make themselves doe-eyed, myopic and beautiful. However, this is not supported by the 16th and 17th century literature, where no mention is ever made of dilated pupils (or any of the effects of parasympathetic blockade). Tournefort (1719) says 'The Italians named this plant Belladonna, which in their language signifies a beautiful woman, because the ladies use it much in the composition of their Fucus [rouge or deceit or cosmetic] or face paint.' Parkinson says that the Italian ladies use the distilled juice as a fucus '... peradventure [perhaps] to take away their high colour and make them looke paler.' I think it more likely that they absorbed atropine through their skin and were slightly 'stoned' and disinhibited, which made them beautiful ladies in the eyes of Italian males. Distribution: Europe, North Africa, western Asia. Culpeper (1650) writes: 'Solanum. Nightshade: very cold and dry, binding … dangerous given inwardly … outwardly it helps the shingles, St Antonie's Fire [erysipelas] and other hot inflammation.' Most of the 16th, 17th and 18th century herbals recommend it topically for breast cancers. Poisonous plants were regarded as 'cold' plants as an excess of them caused death and the body became cold. They were regarded as opposing the hot humour which kept us warm and alive. Poultices of Belladonna leaves are still recommended for muscle strain in cyclists, by herbalists. Gerard (1633) writes that it: 'causeth sleep, troubleth the mind, bringeth madnesse if a few of the berries be inwardly taken, but if more be taken they also kill...'. He was also aware that the alkaloids could be absorbed through the skin for he notes that a poultice of the leaves applied to the forehead, induces sleep, and relieves headache. The whole plant contains the anticholinergic alkaloid atropine, which blocks the peripheral actions of acetylcholine in the parasympathetic nervous system. Atropine is a racemic mixture of d- and l- hyoscyamine. Atropine, dropped into the eyes, blocks the acetylcholine receptors of the pupil so it no longer constricts on exposure to bright light - so enabling an ophthalmologist to examine the retina with an ophthalmoscope. Atropine speeds up the heart rate, reduces salivation and sweating, reduces gut motility, inhibits the vertigo of sea sickness, and is used to block the acetylcholine receptors to prevent the effects of organophosphorous and other nerve gas poisons. It is still has important uses in medicine. Atropine poisoning takes three or for days to wear off, and the hallucinations experienced by its use are described as unpleasant. We have to be content with 'madness', 'frenzie' and 'idle and vain imaginations' in the early herbals to describe the hallucinations of atropine and related alkaloids as the word 'hallucination' in the sense of a perception for which there is no external stimulus, was not used in English until 1646 (Sir T. Browne, 1646). It is a restricted herbal medicine which can only be sold in premises which are registered pharmacies and by or under the supervision of a pharmacist (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Trifolium rubens L. Leguminosae. [Note the Family Leguminosae is preferred over Family Fabaceae as the former allows all the legumes to be in one Family and not three - one Family being the current consensus among botanists]. Red Feather Clover. Distribution: Europe. The white clover, Trifolium repens, is listed as a treatment for arthritis by Linnaeus (1782). This and Trifolium pratense, Red Clover, are the ones most used for pastures. All the clovers have root nodules which fix nitrogen from the air into the soil so have an important role in ensuring soil fertility. Trifolium rubens has the same nitrogen fixing ability, and is used as an ornamental garden plant where it still acts to improve fertility. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Nigella sativa L. Ranunculaceae Love-in-the-mist, Black Cumin, Nutmeg flower, Roman Coriander. Distribution: SW Asia. Culpeper (1650) writes: ‘Nigella seeds, boyled in oil, and the forehead anointed with it, ease pains in the head, take away leprosie, itch, scurf, and helps scald-heads, inwardly taken they expel worms, they provoke urine and the terms, help difficulty of breathing: the smoke of them (being burned) drives away serpents and venomous beasts.’ The seeds are used as a spice, but as might be expected as a member of the family Ranunculaceae, the buttercups, the plant contains a highly poisonous glycoside, in this case called melanthin. The amount of toxicity present in spices is clearly insufficient to cause problems when used as such. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Nigella sativa L. Ranunculaceae Love-in-the-mist, Black Cumin, Nutmeg flower, Roman Coriander. Distribution: SW Asia. Culpeper (1650) writes: ‘Nigella seeds, boyled in oil, and the forehead anointed with it, ease pains in the head, take away leprosie, itch, scurf, and helps scald-heads, inwardly taken they expel worms, they provoke urine and the terms, help difficulty of breathing: the smoke of them (being burned) drives away serpents and venomous beasts.’ The seeds are used as a spice, but as might be expected as a member of the family Ranunculaceae, the buttercups, the plant contains a highly poisonous glycoside, in this case called melanthin. The amount of toxicity present in spices is clearly insufficient to cause problems when used as such. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Cucurbita pepo L., Cucurbitaceae. Distribution: Mexico (extinct) This species is one of the oldest cultivated plants, first grown 11,000 years ago in Mexico, but extinct in the wild. Varieties are selectively bred for their taste, colour and shape. The seeds, ground to a powder are used to kill intestinal tape-worms (Lewis & Elvin-Lewis, 2003). This is a 200-year-old cultivar whose seed has been conserved by the Amish of Pennsylvania, USA. The rind is very thick, but the taste is delicious. This is a 200-year-old cultivar whose seed has been conserved by the Amish of Pennsylvania, USA. The rind is very thick, but the taste is delicious. Seeds approved for use in making herbal medicines in the UK (Herbal Medicine legislation 2013) Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Adonis vernalis L. Ranunculaceae. Pheasant's eye, the golden flowered spring (or vernal) Adonis, is named in memory of Adonis, the Greek god of plants, who disappeared into the earth in the winter and reappeared in the spring. The flowers were said to have sprung from his blood when he was gored to death by a wild boar, but this plant must have been the blood red Adonis aestivalis, the summer Adonis. Distribution: Eurasia to Spain and Sweden. Gerard (1633) recommends it for renal stone and intestinal colic. Lewis & Elvin Lewis (2003) note it is poisonous, containing cardiac glycosides (adonitoxin, cymarin, K-strophanthin) and flavonoids. The UK Medicines and Healthcare Products Regulatory Agency (MHRA)) bans its use for ingestion 'no dose permitted' but allow it to be prescribed by a herbal practitioner on a one-to-one consultation. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Salvia coahuilensis Fernald Lamiaceae Coahuila Sage. Perennial shrub. Distribution: Mexico. Most of the historical medicinal literature is on common sage, Salvia officinalis. The name Salvia meaning 'healthy'. Elizabeth Blackwell (1737) wrote that it had "... all the noble Properties of the other hot Plants more especially for the Head, Memory, Eyes, and all Paralytical Affections. In short, 'tis a Plant endu'd with so many and wonderful Properties, as that the assiduous use of it is said to render Men Immortal" with which Hans Sloane agreed. Its health giving properties were recorded in the aphorisms of the School of Salerno (fl 9-13th century) - quoted in the Decameron [c.1350, translated: Why should man die when Salvia grows in the Garden']. Some salvias, such as Salvia divinorum contain hallucinogenic compounds. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Hepatica nobilis Mill. Ranunculaceae. Liverwort - not to be confused with the lichen of the same name. Distribution: North America. Liverwort (‘liver plant’): discontinued herbal medicine for disorders of the liver. The name and the use to which the Liverworts have been put medicinally is suggested, according to the doctrine of signatures, by the shape of the leaves which are three-lobed, like the liver. It is little used in modern herbalism but was employed in treating disorders of the liver and gall bladder, indigestion etc. It is highly toxic. Hepatica acutiloba was widely used for liver disorders in the 1880s, with up to 200,000 kilos of leaves being harvested per annum to make liver tonics - which eventually caused jaundice. Gerard (1633) calls it Hepaticum trifolium, Noble Liverwort, Golden Trefoile and herbe Trinity and writes: 'It is reported to be good against weakness of the liver which proceedeth from a hot cause, for it cooleth and strengtheneth it not a little. ' He adds ' Baptista Sardus[a Piedmontese physician fl. 1500] commendeth it and writeth that the chiefe vertue is in the root
  • Hepatica nobilis Mill. Ranunculaceae. Liverwort - not to be confused with the lichen of the same name. Distribution: North America. Liverwort (‘liver plant’): discontinued herbal medicine for disorders of the liver. The name and the use to which the Liverworts have been put medicinally is suggested, according to the doctrine of signatures, by the shape of the leaves which are three-lobed, like the liver. It is little used in modern herbalism but was employed in treating disorders of the liver and gall bladder, indigestion etc. It is highly toxic. Hepatica acutiloba was widely used for liver disorders in the 1880s, with up to 200,000 kilos of leaves being harvested per annum to make liver tonics - which eventually caused jaundice. Gerard (1633) calls it Hepaticum trifolium, Noble Liverwort, Golden Trefoile and herbe Trinity and writes: 'It is reported to be good against weakness of the liver which proceedeth from a hot cause, for it cooleth and strengtheneth it not a little. ' He adds ' Baptista Sardus [a Piedmontese physician fl. 1500] commendeth it and writeth that the chiefe vertue is in the root