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  • A voyage to the Levant: or, travels in the principal parts of Asia Minor, the islands of Scio, Rhodes, Cyprus, etc. With an account of the most considerable cities of Egypt, Syria and the Holy Land. Enrich'd with above two hundred copper-plates, wherein are represented the most noted cities, countries, towns and other remarkable things, all drawn to the life / By Corneille le Brunyn. Done into English, by W.F.
  • Ecballium elaterium (L.)A.Rich. Benincaseae Squirting cucumber - when ripe, the seed explodes from its case, squirting some distance. Distribution: Asia, Europe and N. Africa. Contain cucurbitacins which are very bitter, cytotoxic and poisonous. A restricted herbal product, only to be supplied in registered pharmacies or under the supervision of a pharmacist (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Tussilago farfara L. Asteraceae. Coltsfoot. Distribution: Europe, N. Africa, W & N Asia . Culpeper (1650) writes: ‘Tussilago. Coltsfoot. ... they are admirable good for coughs and consumptions of the lungs, shortness of breath etc. It is often used and with great success taken in a tobacco pipe, being cut and mixed with a little oil of Annis seeds.’ It is hepatotoxic genotoxic and carcinogenic due to the pyrrolizidine alkaloids that it contains. It should not be taken internally (Medicines Control Agency, 2002). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Ornithogalum umbellatum L. Hyacinthaceae Star of Bethlehem, Grass lily. Distribution: Central Europe, SW Asia, NW Africa. All parts are poisonous, especially the bulbs. The toxin is a cardiac glycoside with effects similar to digoxin, vomiting, cardiac irregularities and death in humans and livestock. Only used for decoration by Native Americans (it is a non-native plant that has escaped into the wild from cultivation) and called Sleepydick (Moerman, 1998). One of its toxins is Convallotoxin, also present in Lily of the Valley, Convallaria majalis. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Petasites hybridus (L.)G.Gaertn., B.Mey. & Scherb. Asteraceae. Butterbur, Bog rhubarb. Distribution: Europe, NW Asia. Culpeper (1650) writes: “The roots are ... exceeding good in violent and pestilential fevers, they provoke the terms, expel poison, and kill worms.” Modern herbalists recommend it for a wide range of therapies, but it contains pyrrolizidine alkaloids, which are hepatotoxic and cause liver cancers. Nevertheless, in a trial aimed at reducing frequency of migraine attacks, a standardised commercial preparation was well tolerated, and was effective at higher doses, but placebo in this trial reduced migraines by over 50% in 49% of the patients (Neurology 2004
  • Geranium sanguineum L. Geraniaceae Dusky cranesbill. Herbaceous perennial. Distribution: Europe and temperate Asia. County flower of Northumberland. This seems to be the 'Sanguin geranium or Blood Roote', Geranium haematodes/haematites, of Lyte (1578). He writes that it is 'not used in Medicyne.' Parkinson (1640) classifies cranesbills somewhat differently, but says that 'all are found to be effectual both in inward and outward wounds, to stay bleedings, vomitings and fluxes, eyther the decoction of the herbe or the powder of the leaves and roots used as the cause demands. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Primula veris L. Primulaceae. Cowslip, Herba paralysis Distribution: W. Asia, Europe. Fuchs ((1542) quotes Dioscorides Pliny and Galen, with numerous uses, from bruises, toothache, as a hair dye, for oedema, inflamed eye, and mixed with honey, wine or vinegar for ulcer and wounds, for scorpion bites, and pain in the sides and chest, and more. Lobel (1576) calls them Primula veriflorae, Phlomides, Primula veris, Verbascula. Like other herbals of the 16th and 17th century, the woodcuts leave one in no doubt that Primula veris was being written about. However, other translators of Dioscorides (Gunther, 1959 with Goodyear's 1655 translation
  • Petasites hybridus (L.)G.Gaertn., B.Mey. & Scherb. Asteraceae. Butterbur, Bog rhubarb. Distribution: Europe, NW Asia. Culpeper (1650) writes: “The roots are ... exceeding good in violent and pestilential fevers, they provoke the terms, expel poison, and kill worms.” Modern herbalists recommend it for a wide range of therapies, but it contains pyrrolizidine alkaloids, which are hepatotoxic and cause liver cancers. Nevertheless, in a trial aimed at reducing frequency of migraine attacks, a standardised commercial preparation was well tolerated, and was effective at higher doses, but placebo in this trial reduced migraines by over 50% in 49% of the patients (Neurology 2004
  • Abelia x grandiflora R.Br. Caprifoliaceae. Distribution (A. chinensis R.Br. × A. uniflora R.Br.). Mexico, Himalayas to Eastern Asia. Ornamental flowering shrub. The name celebrates the short life of Dr Clarke Abel FRS (1789-1826), one of the first European botanists to collect in China, which he did when attached as physician to the Canton embassy in 1816-17. It has no medicinal uses but is a popular ornamental shrub in the honeysuckle family because it attracts butterflies and has a long flowering period. From June to October it produces a profusion of small, fragrant, pink-flushed, white flowers on long, arching branches. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Polygonum bistorta L. Polygonaceae Bistort, snakeweed, Easter Ledges. Distribution: Europe, N & W Asia. Culpeper: “... taken inwardly resist pestilence and poison, helps ruptures, and bruises, stays fluxes, vomiting and immoderate flowing of the terms in women, helps inflammations and soreness of the mouth, and fastens loose teeth, being bruised and boiled in white wine and the mouth washed with it.” In modern herbal medicine it is still used for a similar wide variety of internal conditions, but it can also be cooked and eaten as a vegetable. The use to relieve toothache, applied as a paste to the affected tooth, seems to have been widespread. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Achillea millefolium L. Asteraceae. Yarrow or sneezewort, the latter because ground up it made a snuff to induce sneezing. Evergreen, herbaceous perennial. Distribution: Europe, Asia and North America. Dioscorides calls it Achilles’ woundwort, sideritis, writing that the ground-up foliage closes bleeding wounds, relieves inflammation and stops uterine bleeding. Gerard (1633) says that put up one’s nose it causes a nosebleed and so stops migraines. Named for the Greek warrior, Achilles, who used this plant for healing wounds – having been taught its properties by his teacher, Chiron the centaur. Millefolium because of the thousands of fronds that make up the leaf, and which, when applied to a bleeding wound, facilitate coagulation by platelets. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Amoenitatum exoticarum politico-physico-medicarum fasciculi V, quibus continentur variae relationes, observationes et descriptiones rerum Persicarum et ulterioris Asiae, multâ attentione / in peregrinationibus per universum Orientem, collectae. Ab auctore Engelberto Kaempfero, D.
  • Amoenitatum exoticarum politico-physico-medicarum fasciculi V, quibus continentur variae relationes, observationes et descriptiones rerum Persicarum et ulterioris Asiae, multâ attentione / in peregrinationibus per universum Orientem, collectae. Ab auctore Engelberto Kaempfero, D.
  • Carthamus tinctorius L. Asteraceae. Safe Flower, False Saffron - Distribution: W. Asia. Dioscorides (in Beck, 2003) notes the seeds as a purgative, but also advises it made up with 30 figs, which must have helped. Gerard (1640) calls it Atractylis flore luteo the yellow distaffe thistle. and follows Dioscorides in its uses, but does get the reader confused with Cnicus benedictus, calling both plants 'wild bastard saffron'. Culpeper makes no mention of it in his early works, but later (1826) have the following: ‘Wild Saffon, or Saf-flower ... accounted a pretty strong cathartic [causing diarrhoea and vomiting], evacuating tough viscid phlegm, both upwards and downwards, and by that means is said to clear the lungs, and help the phthisic [now equated with tuberculosis]. It is likewise serviceable against the jaundice
  • Illicium anisatum L. Illiciaceae Japanese Star Anise. Distribution Japan. This was also called Illicium religiosum and the fruits are toxic. Effects of taking Illicium anisatum tea include epilepsy, vomiting, shakiness and rapid eye movements (US Food and Drug Administration report, 2003). Lindley (1838) and Bentley (1861) thought that I. anisatum was used in cooking, but they were describing the uses of I. verum which is used as a spice in Asia. Illicium anisatum syn. religiosum is 'used to make incense in Japanese and Chinese temples and was called Skimi by Kaempfer. This derives from the Japanese word 'shi-kimi'. The seed pods of both species contain shikimic acid (the name being derived from the Japanese) from which Tamiflu, the antiviral drug was synthesised. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Nigella sativa L. Ranunculaceae Love-in-the-mist, Black Cumin, Nutmeg flower, Roman Coriander. Distribution: SW Asia. Culpeper (1650) writes: ‘Nigella seeds, boyled in oil, and the forehead anointed with it, ease pains in the head, take away leprosie, itch, scurf, and helps scald-heads, inwardly taken they expel worms, they provoke urine and the terms, help difficulty of breathing: the smoke of them (being burned) drives away serpents and venomous beasts.’ The seeds are used as a spice, but as might be expected as a member of the family Ranunculaceae, the buttercups, the plant contains a highly poisonous glycoside, in this case called melanthin. The amount of toxicity present in spices is clearly insufficient to cause problems when used as such. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Nigella sativa L. Ranunculaceae Love-in-the-mist, Black Cumin, Nutmeg flower, Roman Coriander. Distribution: SW Asia. Culpeper (1650) writes: ‘Nigella seeds, boyled in oil, and the forehead anointed with it, ease pains in the head, take away leprosie, itch, scurf, and helps scald-heads, inwardly taken they expel worms, they provoke urine and the terms, help difficulty of breathing: the smoke of them (being burned) drives away serpents and venomous beasts.’ The seeds are used as a spice, but as might be expected as a member of the family Ranunculaceae, the buttercups, the plant contains a highly poisonous glycoside, in this case called melanthin. The amount of toxicity present in spices is clearly insufficient to cause problems when used as such. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Succisia pratensis Greene Asteraceae. Devil’s Bit Scabious, Blue Buttons. Distribution: Europe, W Asia, Africa. Culpeper (1650), under ‘Herbs’ he writes: ‘Succisa, Morsus diobolo, Devil’s Bit. Inwardly taken it easeth the fits of the mother [probably uterine spasm or pain], and breaks wind, taketh away the swellings in the mouth, and slimy phlegm that sticks to the jaws, neither is there a more present remedy in the world, for those cold swellings of the neck, which the vulgar call the Almonds [lymph nodes] of the neck than this herb bruised and applied to them. Folk lore attribute it as a cure-all which was so successful that the Devil bit off the bottom of the roots when he saw it growing down into Hades. However, the roots show no sign of such damage to support the myth. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Primula veris L. Primulaceae Cowslip, Herba paralysis Distribution: W. Asia, Europe. Fuchs ((1542) quotes Dioscorides Pliny and Galen, with numerous uses, from bruises, toothache, as a hair dye, for oedema, inflamed eye, and mixed with honey, wine or vinegar for ulcer and wounds, for scorpion bites, and pain in the sides and chest, and more. Lobel (1576) calls them Primula veriflorae, Phlomides, Primula veris, Verbascula. Lyte (1578) calls them Cowslippe, Petie mulleyn, Verbasculum odoratum, Primula veris, Herbae paralysis and Artheticae. Along with cowslips and oxeslips, he says they are 'used dayly among other pot herbes, but in Physicke there is no great account of them. They are good for the head and synewes ...'. Like other herbals of the 16th and 17th century, the woodcuts leave one in no doubt that Primula veris was being written about. However, other translators of Dioscorides (Gunther, 1959 with Goodyear's 1655 translation
  • Galega officinalis L. Fabaceae. Goat's Rue. Distribution: Central and Southern Europe, Asia Minor. Culpeper (1650) writes that it ‘... resists poison, kills worms, resists the falling sickness [epilepsy], resisteth the pestilence.’ Galega officinalis contains guanidine which reduces blood sugar by decreasing insulin resistance and inhibiting hepatic gluconeogenesis.. Metformin and Phenformin are drugs for type II diabetes that rely on this group of chemicals, known as biguanidines. Its name gala, meaning milk plus ega meaning 'to bring on', refers to its alleged property of increasing milk yield, and has been used in France to increase milk yield in cows. officinalis refers to its use in the offices of the monks, and is a common specific name for medicinal plants before 1600 and adopted by Linnaeus (1753). The fresh plant tastes of pea pods. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Agrimonia eupatoria L. Agrimony, Eupatorium, Maudlein. Perennial herb. The species name comes from king Mithridates Eupator VI of Pontus (132-63 BC) who took regular doses of poison to develop an immunity to them. A 'Mithridate' was a medicine against poisons. Distribution: N. and S. Africa, N. Asia, Europe. '…provokes urine and the terms [periods], dries the brain, opens stoppings, helps the green sickness [iron deficiency anaemia], and profits such as have a cold weak liver outwardly applied it takes away the hardness of the matrix [=uterus] and fills hollow ulcers with flesh' (Culpeper, 1650). Dioscorides (Beck, 2005) recommends mashed leaves in hog's grease for healing scarring ulcers, and the seed in wine for dysentery and serpent bites. Goodyear's 1655 translation of Dioscorides (Gunther 2000) has this as cannabis, which Parkinson (1640) says is in error and summarises the manifold uses from classical authors, from removing splinters to stopping menorrhagia. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Albizia julibrissin Durazz. Fabaceae. Persian silk tree. Called 'shabkhosb' in Persian, meaning 'sleeping tree' as the pinnate leaves close up at night. Tropical tree. Named for Filippo degli Albizzi, an Italian naturalist, who brought seeds from Constantinople to Florence in 1749, and introduced it to European horticulture. The specific epithet comes from the Persian 'gul-i abrisham' which means 'silk flower'. Distribution: South Africa to Ethiopia, Senegal, Madagascar, Asia. Bark is poisonous and emetic and antihelminthic. Various preparations are widely used for numerous conditions and the oxitocic albitocin is abortifacient. However, studies on the seeds and bark of other Albizia species in Africa, demonstrate it is highly toxic, half a kilogram of seeds given to a quarter ton bull, killed it in two hours (Neuwinger, 1996). A useful tree for controlling soil erosion, producing shade in coffee plantations, and as a decorative shade tree in gardens. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Albizia julibrissin Durazz. Fabaceae. Persian silk tree. Called 'shabkhosb' in Persian, meaning 'sleeping tree' as the pinnate leaves close up at night. Tropical tree. Named for Filippo degli Albizzi, an Italian naturalist, who brought seeds from Constantinople to Florence in 1749, and introduced it to European horticulture. The specific epithet comes from the Persian 'gul-i abrisham' which means 'silk flower'. Distribution: South Africa to Ethiopia, Senegal, Madagascar, Asia. Bark is poisonous and emetic and antihelminthic. Various preparations are widely used for numerous conditions and the oxitocic albitocin is abortifacient. However, studies on the seeds and bark of other Albizia species in Africa, demonstrate it is highly toxic, half a kilogram of seeds given to a quarter ton bull, killed it in two hours (Neuwinger, 1996). A useful tree for controlling soil erosion, producing shade in coffee plantations, and as a decorative shade tree in gardens. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Salvia nemorosa L. Lamiaceae Woodland sage. Balkan clary Distribution: Central Europe, Western Asia. Most of the historical medicinal literature is on common sage, Salvia officinalis. The name Salvia meaning 'healthy'. Elizabeth Blackwell (1737) wrote that it had "... all the noble Properties of the other hot Plants more especially for the Head, Memory, Eyes, and all Paralytical Affections. In short, 'tis a Plant endu'd with so many and wonderful Properties, as that the assiduous use of it is said to render Men Immortal" with which Hans Sloane agreed. Linnaeus (1782) also: 'Timor, Languor, Leucorrhoea, Senectus [fear, tiredness, white vaginal discharge, old age]'. Its health giving and immortality conferring properties were recorded in the aphorisms of the School of Salerno (fl 9-13th century) - quoted in the Decameron [c.1350, translated: Why should man die when Salvia grows in the Garden']. Some salvias, such as Salvia divinorum contain hallucinogenic compounds. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Sospensione di commercio con la Turingia, e langraviato d'Assia / Francesco Rossetti.
  • Physalis alkekengi L. Rosaceae Chinese lantern, Winter Cherry, Bladder Cherry Distribution: C & S Europe, W. Asia to Japan Culpeper: In his English Physitian of 1652 writes: Winter Cherry ... are of great use in physic ...’ and recommends them for almost all kidney and urinary problems. In particular he seems to advocate the use of green berries in beer, for preventing kidney stones lodging in the ureters. It is called ‘aikakengi’ in the College’s Pharmacopoeia Londinensis of 1618. Belonging to the family Solanaceae, all its parts are poisonous except the ripe fruit. The green fruit and the rest of the plant contain atropinic compounds and will produce a dry mouth, rapid heart beat, hallucinations, coma and death if enough is taken. As the atropine is only present in the unripe fruit eating one will make the mouth go dry (and it has the most unpleasant taste), but it will also relax the smooth muscle in the wall of the ureter which helps passage of ureteric stones. Culpeper’s observations on its usefulness are supported by more modern observations. When ripe, the orange fruit inside its skeletal outer ‘lantern’ is edible, free of atropine, and delicious. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Vicia faba L. Fabaceae. Broad beans, Fava bean. Distribution: N. Africa, SW Asia. Culpeper (1650) writes: 'Fabarum. Of Beans. Of Bean Cods (or Pods as we in Sussex call them) being burned, the ashes are a sovereign remedy for aches in the joints, old bruises, gout and sciaticaes.’ The beans are perfectly edible for the majority, but 1% of Caucasians, predominantly among Greeks, Italians and people from the Eastern Mediterranean regions, have a genetic trait in that they lack the ability to produce the enzyme glucose-6-phosphate dehydrogenase. As a consequence, eating broad beans or even inhaling the pollen, causes a severe haemolytic anaemia a few days later. This condition is known as favism. The whole plant, including the beans, contains levodopa, a precursor of dopamine, and some patients with Parkinsonism report symptomatic improvement after commencing on a diet that contains these beans regularly. A case of neuroleptic malignant-like syndrome (fever, rigidity, autonomic instability, altered consciousness, elevated creatine phosphokinase levels) consequent on abrupt discontinuation of a diet containing plenty of broad beans, has been described in a patient with Parkinsonism. This is usually seen when patients abruptly discontinue L-dopa therapy. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Physalis alkekengi L. Rosaceae Chinese lantern, Winter Cherry, Bladder Cherry. Distribution: C & S Europe, W. Asia to Japan Culpeper: In his English Physitian of 1652 writes: Winter Cherry ...are of great use in physic ...’ and recommends them for almost all kidney and urinary problems. In particular he seems to advocate the use of green berries in beer, for preventing kidney stones lodging in the ureters. It is called ‘aikakengi’ in the College’s Pharmacopoeia Londinensis of 1618. Belonging to the family Solanaceae, all its parts are poisonous except the ripe fruit. The green fruit and the rest of the plant contain atropinic compounds and will produce a dry mouth, rapid heart beat, hallucinations, coma and death if enough is taken. As the atropine is only present in the unripe fruit eating one will make the mouth go dry (and it has the most unpleasant taste), but it will also relax the smooth muscle in the wall of the ureter which helps passage of ureteric stones. Culpeper’s observations on its usefulness are supported by more modern observations. When ripe, the orange fruit inside its skeletal outer ‘lantern’ is edible, free of atropine, and delicious. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Physalis alkekengi L. Rosaceae Chinese lantern, Winter Cherry, Bladder Cherry. Distribution: C & S Europe, W. Asia to Japan Culpeper: In his English Physitian of 1652 writes: Winter Cherry ...are of great use in physic ...’ and recommends them for almost all kidney and urinary problems. In particular he seems to advocate the use of green berries in beer, for preventing kidney stones lodging in the ureters. It is called ‘aikakengi’ in the College’s Pharmacopoeia Londinensis (1618). Belonging to the family Solanaceae, all its parts are poisonous except the ripe fruit. The green fruit and the rest of the plant contain atropinic compounds and will produce a dry mouth, rapid heart beat, hallucinations, coma and death if enough is taken. As the atropine is only present in the unripe fruit eating one will make the mouth go dry (and it has the most unpleasant taste), but it will also relax the smooth muscle in the wall of the ureter which helps passage of ureteric stones. Culpeper’s observations on its usefulness are supported by more modern observations. When ripe, the orange fruit inside its skeletal outer ‘lantern’ is edible, free of atropine, and delicious. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Physalis alkekengi L. Rosaceae Chinese lantern, Winter Cherry, Bladder Cherry. Distribution: C & S Europe, W. Asia to Japan. Culpeper, in his English Physitian of 1652 writes: Winter Cherry ... are of great use in physic ...’ and recommends them for almost all kidney and urinary problems. In particular he seems to advocate the use of green berries in beer, for preventing kidney stones lodging in the ureters. It is called ‘aikakengi’ in the College’s Pharmacopoeia Londinensis of 1618. Belonging to the family Solanaceae, all its parts are poisonous except the ripe fruit. The green fruit and the rest of the plant contain atropinic compounds and will produce a dry mouth, rapid heart beat, hallucinations, coma and death if enough is taken. As the atropine is only present in the unripe fruit eating one will make the mouth go dry (and it has the most unpleasant taste), but it will also relax the smooth muscle in the wall of the ureter which helps passage of ureteric stones. Culpeper’s observations on its usefulness are supported by more modern observations. When ripe, the orange fruit inside its skeletal outer ‘lantern’ is edible, free of atropine, and delicious. Photographed in the Medicinal Garden of the Royal College of Physicians, London.