concept

Bone

Human stem cell embedded in a 3D matrix, Cryo SEM

Highly invasive human paediatric brain tumour derived cells

3D printed bioglass lattice, SEM

This image is of a bioglass lattice, produced by 3D printing. These lattices show very promising properties for repairing bone defects, as they stimulate bone growth and dissolve over the course of several weeks. 

This image covers an area of 2.5 x 2 mm.

This image shows the cross section and arrangement of osteons and Haversian canals in the bovine bone cortex. Bone is made up of two types of tissue: the compact bone forms a shell around the spongy cancellous bone that makes up the marrow space in the centre. 

Compact bone provides strength and rigidity and is composed of a layered matrix of organic substances and inorganic salts that form around an intricate network of vasculature called Haversian canals (named after the scientist Clopton Havers) shown in blue. Together with the layers of compact bone, they form units called osteons. The tiny blue cells are the osteocytes, or living bone cells that are constantly renewed to make up new bone tissue.

False-coloured cryogenic scanning electron micrograph (Cryo-SEM) of a single human stem cell (centre of image) embedded within a porous hydrogel matrix. The structure and properties of the hydrogel matrix were designed to mimic those of the cell's native environment in the bone marrow. Imaging stem cells in a 3D environment provide valuable insight into the bidirectional physical interactions between a stem cell and its 3D niche. The hydrogel is composed of thiolated hyaluronic acid cross-linked with poly(ethylene glycol) diacrylate. The diameter of the cell is approximately 15 micrometres.

This image shows the cross section and arrangement of osteons and Haversian canals in the bovine bone cortex. Bone is made up of two types of tissue: the compact bone forms a shell around the spongy cancellous bone that makes up the marrow space in the centre. Compact bone provides strength and rigidity and is composed of a layered matrix of organic substances and inorganic salts that form around an intricate network of vasculature called Haversian canals (named after the scientist Clopton Havers) shown in red. Together with the layers of compact bone, they form units called osteons. The tiny blue cells are the osteocytes, or living bone cells that are constantly renewed to make up new bone tissue.

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3D printed bioglass lattice, SEM

Bone

Human stem cell embedded in a 3D matrix, Cryo SEM

Bone

Human stem cell embedded in a 3D matrix, Cryo SEM

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Matrix

Images

Catalogue

3D printed bioglass lattice, SEM

Bone

Human stem cell embedded in a 3D matrix, Cryo SEM

Bone

Human stem cell embedded in a 3D matrix, Cryo SEM

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