concept

Cellular architecture of normal human skin imaged by whole mount tissue microscopy. Human skin has a rich network of white blood cells (specifically dendritic cells, T cells and macrophages) which form sheaths around blood vessels. In this image, T cells (stained for CD3; red) dendritic cells (stained for MHC class II; green) and macrophages (stained for LYVE-1; blue with some cells showing a tinge of green) can be seen. Cell nuclei have been stained with DAPI (grey). This normal cellular architecture is grossly disrupted in diseased skin (see related images). X10 magnification. Scale bar (white) represents 200 micrometres.

Blood vessel with red and white blood cells

Electron micrograph of blood clot,high power

Cellular architecture of normal human skin imaged by whole mount tissue microscopy. Human skin has a rich network of white blood cells (specifically dendritic cells, T cells and macrophages) which form sheaths around blood vessels. In this image, blood vessels (string-like structures stained for CD31; red), lymphatic vessels (ribbon-like structures stained for LYVE-1; blue) and dendritic cells (stained for CD11c; green) can be seen. Macrophages (stained for LYVE-1; blue) are also present. This normal cellular architecture is grossly disrupted in diseased skin (see related images). X10 magnification. Scale bar (white) represents 200 micrometres.

Cellular architecture of normal human skin imaged by whole mount tissue microscopy. Human skin has a rich network of white blood cells (specifically dendritic cells, T cells and macrophages) which form sheaths around blood vessels (string-like structures). A network of lymphatic vessels (ribbon-like structures) is also present. In this image, human skin lymphatic vessels (stained for LYVE-1; blue) and white blood cells comprised of dendritic cells (stained for CD11c; green) and T cells (stained for CD3; red) can be seen. Some macrophages also express the protein LYVE-1 similar to lymphatic vessel cells which can be appreciated as blue cells within and in between the sheaths of white blood cells. This normal cellular architecture is grossly disrupted in diseased skin (see related images). X10 magnification. Scale bar (white) represents 200 micrometres.

SEM of blood corpuscles in clot.

Castration resistant prostate cancer, human tissue

SEM of red blood corpuscles, close-up

Macrophages infected with candida yeast, LM

Macrophages infected with Candida yeast spores, TEM

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SEM of blood corpuscles in clot.

Castration resistant prostate cancer, human tissue

SEM of red blood corpuscles, close-up

Macrophages infected with candida yeast, LM

Macrophages infected with Candida yeast spores, TEM