Human cancer cell

Xenopus cancer kidney cells, prometaphase

Human HeLa cancer cells, mitosis

Human HeLa cancer cell chromosome rosettes

Human HeLa cancer cells, cytokinesis

Xenopus cancer kidney cells, interphase

Human HeLa cancer cell, metaphase.

Human HeLa cancer cells, metaphase

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A deconvolved wide-field fluorescence microscope image of human HeLa cancer cells undergoing mitosis - various stages shown - bottom left, metaphase; top anaphase; bottom right telophase and far right early interphase. The chromosomes show up white with a DAPI stain. The cytoskeleton/spindle microtubules are blue/purple. The red is Aurora B, a protein kinase involved in the polymerisation/depolymerisation of microtubules during mitosis.

A deconvolved wide-field fluorescence microscope image of human HeLa cancer cells undergoing cytokinesis (cell division). The red fluorescence is the microtubules of the cytoskeleton. The white is actin. The blue is DNA (DAPI stain). The green is Aurora B, a protein kinase involved in the polymerisation/depolymerisation of the microtubules during mitosis and cytokinesis. The yellow area is the overlap between the red and the green fluorescence.

A deconvolved wide-field fluorescence microscope image of a human HeLa cancer cell undergoing aberrant mitosis - the spindle has three poles. The microtubules of the spindle show yellow. The purple is Aurora B, a protein kinase involved in the polymerisation/depolymerisation of the microtubules. The centromeres are blue.

Human HeLa cancer cell, tripolar mitosis

A deconvolved wide-field fluorescence microscope image of human HeLa cancer cells undergoing cytokinesis (cell division). The chromosomes are red (DAPI stain for DNA). The microtubules of the cytoskeleton/spindle are purple, and the actin white. The green is Aurora B, a protein kinase involved in the polymerisation/depolymerisation of the microtubules during mitosis and cytokinesis.

A composite image derived from deconvolved wide-field fluorescence microscope images of chromosome prometaphase "rosettes". The chromosomes have been stained with DAPI stains in various colours (orange, blue, mauve and turquoise). The coloured blobs represent the location of probes for centromeres and Aurora B, a protein kinase involved in polymerisation/depolymerisation of microtubules in the spindle during mitosis, and associated with the centromeres.

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Aurora B

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Human HeLa cancer cells, mitosis

Human HeLa cancer cells, cytokinesis

Human HeLa cancer cell, tripolar mitosis

Human HeLa cancer cells, cytokinesis

Human HeLa cancer cell chromosome rosettes

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Wellcome uses cookies.

Aurora B

Images

Works

Human HeLa cancer cells, mitosis

Human HeLa cancer cells, cytokinesis

Human HeLa cancer cell, tripolar mitosis

Human HeLa cancer cells, cytokinesis

Human HeLa cancer cell chromosome rosettes

Wellcome Collection

Today’s opening times