15 results
- Books
Synthetic substitutes for opiate alkaloids : a feasibility study / Joseph Cochin, Louis Harris.
Cochin, JosephDate: [1975]- Ephemera
Opiates are used as painkillers ... / Crew 2000.
Date: [1999?]- Archives and manuscripts
Dixon, Walter Ernest, and Myers, (George) Norman
Dixon, Walter E. (Walter Ernest), 1871-1931.Date: 1865-1949Reference: GC/155- Ephemera
A cure is guaranteed in consumption! : is possible in the last stages of the disease : treatment upon entirely new principles!! No cod liver oil! No inhalation! No local treatment! No stimulation or tonics! No opiates... / Erwin L. Jones.
Jones, Erwin L.Date: [between 1800 and 1899]- Archives and manuscripts
Volume 1. 'Technology Transfer in Britain: The Case of Monoclonal Antibodies; Self and Non-self: A History of Autoimmunity; Endogenous Opiates; The Committee on Safety of Drugs'
The Wellcome Trust Centre for the History of Medicine at UCLDate: 1992-1997Reference: GC/253/A/1Part of: Wellcome Witnesses to Twentieth Century Medicine Seminars- Archives and manuscripts
Society for the Study of Addiction to Alcohol and other Drugs
Society for the Study of Addiction to Alcohol and other DrugsDate: 1904-1987Reference: SA/SSA- Books
The story of medicine : from bloodletting to biotechnology / by Mary Dobson.
Dobson, Mary J.Date: 2013- Archives and manuscripts
Glatt, Max Meier (1912-2002)
Glatt, Max Meier MD, DSc, FRCP, FRCPsych, DPM (1912-2002)Date: c. 1950s-1990sReference: PP/MXG- Digital Images
- Online
Papaver somniferum L. Papaveraceae Opium Poppy Distribution: Asia minor, but has been dated to 5000BC in Spanish caves. Now grows almost everywhere. The oldest medicine in continuous use, described in the Ebers' papyrus (1550 BC), called Meconium, Laudanum, Paregoric and syrup of poppies. Culpeper (1650) on Meconium '...the juyce of English Poppies boyled till it be thick' and 'I am of the opinion that Opium is nothing else but the juyce of poppies growing in hotter countries, for such Opium as Authors talk of comes from Utopia.[he means an imaginary land, I suspect]’]. He cautions 'Syrups of Poppies provoke sleep, but in that I desire they may be used with a great deal of caution and wariness...' and warns in particular about giving syrup of poppies to children to get them to sleep. The alkaloids in the sap include: Morphine 12% - affects ?-opioid receptors in the brain and causes happiness, sleepiness, pain relief, suppresses cough and causes constipation. Codeine 3% – mild opiate actions – converted to morphine in the body. Papaverine, relaxes smooth muscle spasm in arteries of heart and brain, and also for intestinal spasm, migraine and erectile dysfunction. Not analgesic. Thebaine mildly analgesic, stimulatory, is made into oxycodone and oxymorphone which are analgesics, and naloxone for treatment of opiate overdose – ?-opioid receptor competitive antagonist – it displaces morphine from ?-opioid receptors, and constipation caused by opiates. Protopine – analgesic, antihistamine so relieves pain of inflammation. Noscapine – anti-tussive (anti-cough). In 2006 the world production of opium was 6,610 metric tons, in 1906 it was over 30,000 tons when 25% of Chinese males were regular users. The Opium wars of the end of the 19th century were caused by Britain selling huge quantities of Opium to China to restore the balance of payments deficit. Laudanum: 10mg of morphine (as opium) per ml. Paregoric: camphorated opium tincture. 0.4mg morphine per ml. Gee’s Linctus: up to 60 mg in a bottle. J Collis Browne’s chlorodyne: cannabis, morphine, alcohol etc. Kaolin and Morph. - up to 60 mg in a bottle. Dover’s Powders – contained Ipecacuana and morphine. Heroin is made from morphine, but converted back into morphine in the body (Oakeley, 2012). One gram of poppy seeds contains 0.250mgm of morphine, and while one poppy seed bagel will make a urine test positive for morphine for a week, one would need 30-40 bagels to have any discernible effect. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley- Digital Images
- Online
Papaver somniferum L. Papaveraceae Opium Poppy Distribution: Asia minor, but has been dated to 5000BC in Spanish caves. Now grows almost everywhere. The oldest medicine in continuous use, described in the Ebers' papyrus (1550 BC), called Meconium, Laudanum, Paregoric and syrup of poppies. Culpeper (1650) on Meconium '...the juyce of English Poppies boyled till it be thick' and 'I am of the opinion that Opium is nothing else but the juyce of poppies growing in hotter countries, for such Opium as Authors talk of comes from Utopia [he means an imaginary land, I suspect]’. He cautions 'Syrups of Poppies provoke sleep, but in that I desire they may be used with a great deal of caution and wariness...' and warns in particular about giving syrup of poppies to children to get them to sleep. The alkaloids in the sap include: Morphine 12% - affects ?-opioid receptors in the brain and causes happiness, sleepiness, pain relief, suppresses cough and causes constipation. Codeine 3% – mild opiate actions – converted to morphine in the body. Papaverine, relaxes smooth muscle spasm in arteries of heart and brain, and also for intestinal spasm, migraine and erectile dysfunction. Not analgesic. Thebaine mildly analgesic, stimulatory, is made into oxycodone and oxymorphone which are analgesics, and naloxone for treatment of opiate overdose – ?-opioid receptor competitive antagonist – it displaces morphine from ?-opioid receptors, and reverses the constipation caused by opiates. Protopine – analgesic, antihistamine so relieves pain of inflammation. Noscapine – anti-tussive (anti-cough). In 2006 the world production of opium was 6,610 metric tons, in 1906 it was over 30,000 tons when 25% of Chinese males were regular users. The Opium wars of the end of the 19th century were caused by Britain selling huge quantities of Opium to China to restore the balance of payments deficit. Laudanum: 10mg of morphine (as opium) per ml. Paregoric: camphorated opium tincture. 0.4mg morphine per ml. Gee’s Linctus: up to 60 mg in a bottle. J Collis Browne’s chlorodyne: cannabis, morphine, alcohol etc. Kaolin and Morph. - up to 60 mg in a bottle. Dover’s Powders – contained Ipecacuana and morphine. Heroin is made from morphine, but converted back into morphine in the body (Oakeley, 2012). One gram of poppy seeds contains 0.250mgm of morphine, and while one poppy seed bagel will make a urine test positive for morphine for a week, one would need 30-40 bagels to have any discernible effect. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley- Archives and manuscripts
Dr Elizabeth ("Betty") Tylden (1917-2009) and Dr George Douglas Morgan (1899-1985
Tylden, Dr Elizabeth (1917-2009), MA, MB BCh, MRCPsych, FRSM, MEWIDate: 1930s-1990sReference: PP/TYL- Ephemera
Drug advertising ephemera. Box 9.
- Archives and manuscripts
Holmes, Edward Morell (1843-1930), botanist and lecturer in materia medica
Holmes, Edward Morell, 1843-1930.Date: 1876-1930Reference: MSS.2867-2932, 7961 & WMS/Amer.145-148- Digital Images
- Online
Papaver somniferum seed
Dr Henry Oakeley- Videos
Pain, pus and poison.
Date: 2013