Clinical diagnosis : the bacteriological, chemical, and microscopical evidence of disease / by Rudolf v. Jaksch.

  • Jaksch, Rudolf v., 1855-1947.
Date:
1899
Catalogue details

Licence: Public Domain Mark

Credit: Clinical diagnosis : the bacteriological, chemical, and microscopical evidence of disease / by Rudolf v. Jaksch. Source: Wellcome Collection.

Provider: This material has been provided by the Francis A. Countway Library of Medicine, through the Medical Heritage Library. The original may be consulted at the Francis A. Countway Library of Medicine, Harvard Medical School.

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    Laderiburg and Abel,9'3 is probably identical with sethylenimin, or diaethylendiamin,94 though this identity is disputed by Th. Koh?i95 on very good grounds. Leyden believed that the crystals were the exciting cause of the asthmatic paroxysm. Friedreich96 and Zenker found them in expec- torated fibrin-coagula, and Bizzozero97 in the sputum of acute bronchitis from patients who were not subject to asthma. The author can corro- borate the statement of these observers. [Trouj)9S asserts also that neither spirals nor Charcot-Leyden crystals are pathognomonic of any one disease, but points out that the former are invariably to be found in asthmatic sputa, and by their presence cause the paroxysms. A charac- teristic feature of the conditions in which both spirals and crystals are found is marked desquamation of the mucous surface of the bronchioles, and the same author refers the origin of Charcot-Leyden crystals to the altered cells which are thus stripped off.] Fig. 64.—Charcot-Leyden Crystals, from the Sputum of an Asthmatic Patient (eye-piece III., objective VII., Hartnack). 2. Hsematoidin Crystals.—Crystals of hsematoidin, described by Virchoio, Friedreich, and Schultze, occur in the sputum as ruby-red rhombic prisms, either solitary or in groups, or as needles or clusters of needles. These crystals, or fragments of them, are often found enclosed within the substance of white blood-corpuscles (fig. 53, e). Under such circumstances hsematoidin is also seen, either free or in the interior of the white blood-corpuscles, as a mass of pigment in which no trace of the crystalline formation can be discovered. When hsematoidin crystals appear in the expectoration, we may conclude that blood has been effused and suffered to remain for some time in the air-passages, or that an abscess has perforated the lung. They occur most abundantly, therefore, in phthisis after haemoptysis, when pulmonary clots are in process of absorption, very often in pulmonary abscess, and when an abscess or suppurating hydatid cyst has discharged into the lung. When the crystals are contained in cells, they point to a previous hcemorrhage; but rohen free licematoidin is