The constituents of chaulmoogra seeds / by Frederick B. Power and Frank H. Gornall.

  • Power, Frederick B. (Frederick Belding), 1853-1927
Date:
[1904]
Catalogue details

Licence: In copyright

Credit: The constituents of chaulmoogra seeds / by Frederick B. Power and Frank H. Gornall. Source: Wellcome Collection.

    15/20 (page 850)
    14*93 grams in 100 c.c. of chloroform gave aD + 3°5' in a 50 mm. tube, whence [a]D +41*5°. 0*0870 gave 0-2398 C02 and 0-0886 H20. C = 75*2 ; H = 11*3. 0-1006 „ 0-2774 C02 „ 0-1016 H20. 0 = 75*2; H = ll*2 percent. 1 *0014 required NaOH equivalent to 39 c.c. of a decmormal solu¬ tion, which is the calculated amount for 016H3202. 0-6972 required 0*6163 iodine. 1 = 88*4 per cent. From these data it is probable that this fraction consists largely of an acid or acids having the formula C16H2802 or C14H2402, belonging to the series CnH2n-402 with one ethylenic linking. Fraction melting at 43—44°.—This fraction distilled between 224° and 234°/ll —12 mm. 12-66 grams in 100 c.c. of chloroform gave aD 4-3°34' in a 50 mm. tube, whence [a]D +56-3°. 0*0884 gave 0*2430 C02 and 0*0884 H20. C = 75-0; H = 1M. 0*1173 „ 0-3243 C02 „ 0*1172 H20. C = 75*4 • H = 11*1 per cent. 1-0962 required NaOH equivalent to 42*6 c.c. of a decinormal solu¬ tion, instead of 39*1 c.c. or 42*8 c.c., the calculated amounts for Ci8H3202 or C16H3202 respectively. 0*6948 required 0’6700 iodine. 1 = 96*4 per cent. The probable composition of this fraction may be indicated by the remarks appended to the one preceding it. Fraction melting at 36—38°.—This fraction distilled between 225° and 235°/ll—12 mm. 11*6 grams in 100 c.c. of chloroform gave aD + 2°54' in a 50 mm. tube, whence [a]D +50°. 0*1060 gave 0*2922 C02 and 0*1054 H20. C = 75*2; H = 11*0. 0*1070 „ 0*2940 C02 „ 0*1054 H20. C = 74*9 ; H= 11-0 per cent. 1*0002 required NaOH equivalent to 37*5 c.c. of a decinormal solu¬ tion, instead of 35*7 c.c. or 39 c.c., the calculated amounts for C18H3„02 or C16H3202 respectively. 0*6942 required 0-6460 iodine. 1 = 93*1 per cent. From these data, the composition of this fraction would appear to be essentially that of the preceding one. The Oily Acid separated by Pressure.—This fraction distilled between 218° and 227°/10 mm. as an almost colourless oil, which, on cooling, formed a nearly solid cake melting at 20°. 14*14 grams in 100 c.c. of chloroform gave aD + 3°4' in a 50 mm. tube, whence [a]D +43*4°.