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Human metaphase, translocation, cosmid probe
- Wessex Reg. Genetics Centre
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Credit: Human metaphase, translocation, cosmid probe.
Credit: Wessex Reg. Genetics Centre.
Attribution 4.0 International (CC BY 4.0)
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Description
Human chromosomes at metaphase, highlighted with
fluorescent probes that bind to specific sequences
of DNA. This cell is from the amniotic fluid of a
patient with an unbalanced translocation between
chromosomes 4 and 9, t(4,9). The bcr cosmid (red)
is present on both chromosome 9 homologues, and also
at the distal tip of the short arm of the der(4) -
chromosome 4.
Image by Dr John Crolla.
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