On necrosis : being an experimental inquiry into the agency ascribed to the absorbents, in the removal of the sequestrum : with some observations concerning the adhesion of living to dead bone / by George Gulliver.

Date:
1838
Catalogue details

Licence: Public Domain Mark

Credit: On necrosis : being an experimental inquiry into the agency ascribed to the absorbents, in the removal of the sequestrum : with some observations concerning the adhesion of living to dead bone / by George Gulliver. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    ing 9.8 grains, was introduced into the subcutaneous cellular substance of a dog’s leg, and allowed to re- main there three months. The wound soon healed, and continued well for nearly two months, when a small ulcerated aperture formed in the cicatrix, in consequence of the bone having been moved about roughly, and suppuration ensued. The bone was found to have undergone no alteration whatever. EXPERIMENT VIII. A thin portion of the shaft of the human humerus was placed in the subcutaneous cellular tissue of a dog’s leg, and allowed to remain there four months. The wound soon healed, and continued sound till the animal was killed. The bone had suffered no change whatever: it adhered slightly to the cellular sub- stance, so as to stretch out the filaments of the latter as the bone was pulled away. EXPERIMENT IX. A piece of the metacarpal bone of a rabbit was introduced into the medullary canal of the tibia of another rabbit, where it remained seven weeks. The wound readily healed, and the animal continued healthy and active until it was killed. The foreign bone, which I had not weighed pre- viously to the experiment, had undergone no appre- ciable change: it was imbedded in a soft substance, which I have shewn to be highly vascular by injec- tion. The tibia was simply thickened. (E. P. B.