Organic materia medica and therapeutics : in accordance with the sixth revision of the United States Pharmacopoeia / by James Young Simpson.

  • Simpson, James Young, 1811-1870.
Date:
1885
Catalogue details

Licence: Public Domain Mark

Credit: Organic materia medica and therapeutics : in accordance with the sixth revision of the United States Pharmacopoeia / by James Young Simpson. Source: Wellcome Collection.

Provider: This material has been provided by the Harvey Cushing/John Hay Whitney Medical Library at Yale University, through the Medical Heritage Library. The original may be consulted at the Harvey Cushing/John Hay Whitney Medical Library at Yale University.

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    of QuiNiN/rc valeeianas.—Soluble in 100 parts of water and 5 parts of alcohol at normal temperatures. Soluble in 40 parts of boiling water, 1 part of boiliug alcohol, and slightly soluble in ether. of ciNCHONiDiNiE sulphas.—Soluble in 100 parts of water and 71 parts of alcohol at normal temperatures. Soluble in 4 parts of boiling water and 12 parts of boiling alcohol, and freely soluble in acidulated water. of QuiNiDiNiE sulphas.—Soluble in 100 parts of water and in 8 parts of alcohol at the normal temperatures. Soluble in 7 parts of boiling water and very soluble in boiling alcohol. of chinoidin or quinoidin.—Almost insoluble in water, freely soluble in alcohol, chloroform, and dilute acids ; partially sol- uble in ether. GENERAL ACTION. Cerebral stimulant. Spinal depressant. Cardiac depress- ant. Bitter tonic. Gastric stimulant. Intestinal astringent. Oxytocic. Antipyretic. Antiperiodic. Antiseptic. Local irritant. Synergists.—Bitter tonics, iron, arsenic, acids, and all sub- stances promoting constructive metamorphosis. Antagonists and Incompatibles.—Tannic acid, alkalies, alka- line carbonates, alkaline earths, preparations of iodine either render insoluble or precipitate the alkaloids of cinchona. Mer- cury, the iodides, and salts of copper, zinc, and lead are all antagonistic, because they favor destructive metamorphosis. PHYSIOLOGICAL ACTION. Nervous System: Brain.—This drug is supposed by authorities to cause cer- ebral hyperemia, thus giving tinnitus aurium with partial deafness, giddiness, and vertigo, with a feeling of fulness in the head. Amblyopia and amaurosis may be caused by full doses. Spinal Cord.—It reduces reflex irritability of the spinal cord. Circulatory System : Heart.—In small doses it accelerates the heart's action, but