The thyroid and parathyroid glands / by Hubert Richardson.

  • Richardson, Hubert.
Date:
1905
Catalogue details

Licence: Public Domain Mark

Credit: The thyroid and parathyroid glands / by Hubert Richardson. Source: Wellcome Collection.

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    germs. and later 6.0 grms. thyroid sicca daily. There was an increased elimination if nitrogen, sodium chlorid and phosphoric acid. He then removed the thyroids and con- tinued the administration of the thyroid sicca, the nitrogen and sodium chlorid elimination was further increased, but the phosphoric acid was diminished. The nitrogen elim- ination in the unoperated animal rose from 3.04 to 3.8 and from 3.4 to 4.15 and in the operated animal from 3.61 to 0.300. Magnus Levy found that the amount of oxygen utilized by a subject at rest was 3.1 to 5.36 cem., while in the obese it was only 2.82 (v. Noorden found 2.64). «By the administration of thyroid he could raise the O used from 2.26 to 2.36 on the fifteenth day and to 2.55 on the nineteenth day, the loss of weight in the nineteen days being 4 kg. Theile and Nehrung raised the O from 2.87 to 3.48, or 20 per cent; v. Noorden raised the-O used 21 per cent, which lasted fourteen days after the thyroid feeding was suspended. Magnus Levy treated a myx- edematous patient with thyroid tablets, thyroantitoxin and iodothyrin. With the tablets the patient lost weight from 42 to 39.2 kg., the pulse rose from 60 to 120, temperature from 36.2 to 37.5, the O used from 1.22 to 2.15, the respira- tion quotient sank from 0.85 to 0.71. With Fraenkel’s antitoxin the amount of O used was not increased nor did the pulse rate increase, the body weight did not fall but increased 1 kg. The iodothyrin produced about the same effect as the tablets, the O rose from 1.3 to 1.98, the respi- ration quotient fell from 0.83 to 0.74, the pulse rate rose from 60 to 100, the body weight fell from 44.2 to 41.9 kg. Sttive found the O used increased in a healthy subject by the administration of thyroid tablets 20 to 23 per cent, while the increase of CO, eliminated was somewhat less. Voit arrived at the same conclusions. Venehren experimented with three normal young men,