A case of gastric tetany, with an account of the microscopic appearances found in the medulla and spinal cord / by Walter K. Hunter, M.D., B.Sc., Assistant Physician, Royal Infirmary ... from Dr. Lindsay Steven's Wards in the Glasgow Royal Infirmary.

  • Hunter, Walter King.
Date:
[1899]
Catalogue details

Licence: Public Domain Mark

Credit: A case of gastric tetany, with an account of the microscopic appearances found in the medulla and spinal cord / by Walter K. Hunter, M.D., B.Sc., Assistant Physician, Royal Infirmary ... from Dr. Lindsay Steven's Wards in the Glasgow Royal Infirmary. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

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    had the pigment granules collected together into one part of the plasma, the rest being tilled with well-stained Nissl bodies (cells h, c, d, e, u). And it is to be noted that in these cells the presence of large masses of pigment did not seem to atlect the staining of the Nissl bodies, for, even when only a few of these bodies remained, their staining was quite intense (cells o, p, r, s). In the majority of the cells the pigment granules seem first to be deposited as a compact little mass at one pole of the cell. This pigment mass seems gradually to increase in size, displacing, as it does so, the adjacent Nissl bodies till, ultimately, the whole cell plasma is tilled with pigment and no Nissl bodies re- main. At the part of the cell where pigment and Nissl bodies join there was a certain overlapping of the two elements, and there the Nissl bodies seemed smaller in size, as if the invading pigment was breaking them up (cells h, d, i). With a lower power (-jtth inch) the dividing line between pigment and Nissl bodies seemed sharply defined, but with the higher power (xVf^^ inch) the above-mentioned fragmentation of the chromatophile elements could usually, though not always, be made out. It could not be said that the Nis.sl bodies at this line of contact were individu- ally more deeply stained than at other parts of the cell, and so I did not recognize in these cells the “ sclerozed zone” as described by Be van Lewis. Neither could I find any cells corresponding to Bevan Lewis’s first stage of pigmentation—cells slightly swollen, and staining deeply. Certainly some cells stained fairly deeply but they did not seem swollen, indeed they .seemed quite normal. It was difficult to determine with any certainty the effect of the pigment on the cell nucleus. But as far as I could make out the nucleus suffered in much the same way as did the Nissl bodies. That is to say, the nucleus seemed unaffected till actually invaded by the pigment granules, or, till the whole cell plasma was replaced by pigment, when the nucleus could sometimes be seen faintly outlined towards the centre of the cell (cells j, n). Probably, how- ever, the nucleus was sometimes obscured by the surrounding
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