The malarial fevers of Baltimore : An analysis of 616 cases of malarial fever, with special reference to the relations existing between different types of haematozoa and different types of fever / by William Sydney Thayer and John Hewetson.

  • Thayer, William Sydney, 1864-1932.
Date:
1895
Catalogue details

Licence: Public Domain Mark

Credit: The malarial fevers of Baltimore : An analysis of 616 cases of malarial fever, with special reference to the relations existing between different types of haematozoa and different types of fever / by William Sydney Thayer and John Hewetson. Source: Wellcome Collection.

Provider: This material has been provided by the Augustus C. Long Health Sciences Library at Columbia University and Columbia University Libraries/Information Services, through the Medical Heritage Library. The original may be consulted at the the Augustus C. Long Health Sciences Library at Columbia University and Columbia University.

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    more reddish brown); the outlines of ilie body in general, which are quite clear and sharply defined in the quartan parasite, are, in the tertian, very indistinct. The dancing of the granules is also much more active in the tertian organism. With the growth of the quartan parasite the red corpuscle remains about its normal size, or, indeed, tends to shrink about the body, while the decolorization does not occur until later on, so that the organism may have reached almost its complete development without any particular change in tlie color of the red disc. In tertian infections, however, the corpuscle begins to be decolorized early in the development of the parasite, and instead of tending to shrink about the body, it becomes considerably expanded and swollen, so that at the time of complete development of the parasite it may be very much larger than its normal neighbor. The full grown tertian organism is then somewhat larger than the quartan parasite. In segmentation also there are material differences between the organism of tertian and that of quartan fever. Golgi describes two distinct varieties : (1). The pigment gathers in the centre of the body, while a certain differentiation may be made out between the peripheral clear proto- plasm and the central part with the pigment; indications of a radial striation begin to appear in the peripheral clear protoplasm, which eventually becomes divided into from fifteen to twenty small hyaline segments. The differences between this mode of segmentation and that of the parasite of quartan fever are, according to Golgi: (a). The greater number of segments, from fifteen to twenty. (6). The difference in the size of the individual segments which are smaller in the tertian parasite. (c). The absence of the central refractive spot in the tertian par- asite. - (rf). The fact that the pigment which gatliers in the centre appears here to be contained in a protoplasmic body. These pigmented bodies Golgi believes to be for the most part, taken up by phagocytic leucocytes, though he does not feel sure that some of them may not remain in function and produce other bodies. (2). This variety of segmentation differs from the first in that after the pigment has collected into a small clump, the whole mass of the protoplasm becomes divided into small round bodies, which do not