Manual of veterinary microbiology / by Professors Mosselman and Liénaux ; translated and edited by R.R. Dinwiddie.

  • Mosselman, Gustave.
Date:
1894
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Manual of veterinary microbiology / by Professors Mosselman and Liénaux ; translated and edited by R.R. Dinwiddie. Source: Wellcome Collection.

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    insertion. Derrnic insertion gives uncertain results, the virulent matter requiring to be brought into the cellular tissue in order to act efficaciously. On the other hand, hypodermic injection supplies the best conditions for the evolution of the virus. For the reception of the pulmonary serosity the cellular tis- sue of the tail should be selected in preference to all other regions; as has already been said the conse- quences of inoculation are often very severe in regions where the connective tissue is loose and abundant. In the tissue of the tail, one or two drops of the serosity are sufficient. It is well to make a second vaccination a few weeks later; this may be made in an interdicted region although this procedure can not be recommended, especially when the reaction to the first inoculation has been insufficient. With the view of obviating the accidents which occasionally follow the caudal inoculation some ex- perimenters, including Professor-Director Degive, have had recourse to intravenous injection; this method procures a solid immunity, but requires special care in order to avoid accidental contact of the virus with the cellular tissue which surrounds the vein, an accident which may result in a serious, perhaps fatal, engorgement. Larger doses may be introduced into the veins than into the cellular tissue. For the practice of Willemsian inoculation it is essential that fresh virus be employed. This is ob- tained by making a clean incision of a diseased lung with an aseptic knife and collecting the. serosity which flows spontaneously from regions in which the inflammation is most recent. As such a lung is not al-