The action of an active principle from apocynum / by H.H. Dale and P.P. Laidlaw.

  • Dale, Henry Hallett, 1875-1968.
Date:
1909
Catalogue details

Licence: Attribution 4.0 International (CC BY 4.0)

Credit: The action of an active principle from apocynum / by H.H. Dale and P.P. Laidlaw. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    May 7th. 9.51 a.m. Cat quite normal. Heart-beat 170 per minute when quiot. 2 mg. Apocy- 10.20 a.m. 10.22 a.m. 10.55 a.m. 5.10 p.m. namarin in capsule given by mouth. Heart-beat 120 per minute. Regular and forcible. No signs of nausea. Cat suddenly vomited without any premonitory symptoms. Heart-boat 140 per minute. No further sickness. Heart-beat 148-152 per minute. Cat appears to be quite well. 2 mg. Apocy- namarin in capsule given by mouth. 5.55 p.m. Heart-beat 100-112 per minute. The animal is quiet. May 8th. 10.20 a.m. Cat appears to be quite well. Heart-beat 140 when the animal is quiet; it becomes a little more rapid after walking about the laboratory. 10.23 a.m. 10.58 a.m. 11.30 a.m. 2 mg. Apocynamarin in capsule given by mouth. Heart-beat 128 per minute. No signs of discomfort or uneasiness. Defaecation and micturition. Heart-boat much the same. No second dose was given on this day. May 9th. 11.45 a.m. 11.50 a.m. 12.24 p.m. 1.10 p.m. 3.-10 p.m. Cat seems well. Heart-beat 176-184 per minute. 2 mg. Apocynamarin in capsule given by mouth. Heart-beat 144 per minuto. No symptoms of discomfort or nausea. Heart-boat 156 per minute. Micturition. Heart-boat 148 per minute. Cat seems quito woll. 2 mg. Apocynamarin in capsule given by mouth. 3.45 p.m. Heart-boat 140 per minute. 4.25-4.35 p.m. Four readings of heart-boat during this period were, 128, 124, 136, 140. May 10th. 9.50 a.m. 10.0 a.m. 10.30 a.m. 5.0 p.m. 5.35 p.m. Heart-beat 148 per minute. 2 mg. Apocynamarin in capsule given by mouth. Heart-boat 108 per minute. Heart-boat 136 per minute. 2 mg. Apocynamarin in capsule given by mouth. Heart-boat 108-112 per minute. May 11th. 9.55 a.m. 10.45 a.m. 4.44 p.m. 6.0 p.m. Heart-beat 148 per minute. 2 mg. Apocynamarin in capsule givon by mouth. The cat basking in sunlight. Heart-beat 128. Heart-beat 140 por minute. 2 mg. Apocynamarin in capsulo givon by mouth. Heart-beat 108 per minute. May 12th. 9.45 a.m. Cat appears to be quite well. Heart-boat 148 por minute. 2 mg. Apocy- 5.15 p.m. 5.58 p.m. namarin in capsulo given by mouth. Hoart-beat 148 per minute. 2 mg. Apocynamarin in capsule given by mouth. Hoart-beat 140 per minute. May 13th. 10.0 a.m. Hoart-beat 128 por minute when asleep. 148 when disturbed. 10.26 a.m. 2 mg. Apocynamarin in capsule given by mouth. 11.20 a.m. Heart-boat 120 per minuto. 2.5 p.m. Heart-boat 144 per minuto. 2 mg. Apocynamarin in capsule given by mouth. 2.25 p.m. Hoart-beat 120 per minute. May 14th. Heart-beat 148. Cat appears to be quito well. Exporimont discontinued. May 18th. Hoart-beat 180 por minute. Cat appears to bo quite normal.