Notice of a new anaesthetic agent, as a substitute for sulphuric ether in sugery and midwifery / By J.Y. Simpson.

  • James Young Simpson
Date:
1847
Catalogue details

Licence: Public Domain Mark

Credit: Notice of a new anaesthetic agent, as a substitute for sulphuric ether in sugery and midwifery / By J.Y. Simpson. Source: Wellcome Collection.

Provider: This material has been provided by the Harvey Cushing/John Hay Whitney Medical Library at Yale University, through the Medical Heritage Library. The original may be consulted at the Harvey Cushing/John Hay Whitney Medical Library at Yale University.

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    possibility of producing for irihalation vaporizable or volatile preparations of some of our more active and old established medicines: and I have had, during the summer and autumn, ethereal tinctures, &c, of several potent drugs, manufactured for me, for expe- riment, by Messrs Duncan, Flockhart, & Co., the excellent chemists and druggists of this city. Latterly, in order to avoid, if possible, some of the inconveniences and objections pertaining to sul- phuric ether,—(particularly its disagreeable and very persistent smell, its occasional tendency to irritation of the bronchi during its first inspirations, and the large quantity of it occasionally required to be used, more especially in protracted cases of labour,)—I have tried upon myself and others the inhalation of differ- ent other volatile fluids, with the hope that some one of them might be found to possess the advantages of ether, without its disadvantages. For this purpose, I selected for experiment and have inhaled several chemical liquids of a more fragrant or agreeable odour, such as the chloride of hydro-carbon (or Dutch liquid), acetone, nitrate of oxide of ethyle (nitric ether), benzin, the vapour of iodoform, &c* * In talking over, with different chemists, what fluids might be suffi- ciently volatile to be respirable, and hence deserving of being experi- mented upon, Mr Waldie first named to me the Perchloride of Formyle as worthy, among others, of a trial;—Dr Gregory suggested a trial of
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