Fibrin, its origin and development in the animal organism, and its relation to life, health, longevity, and disease / by John Goodman.

  • Goodman, J. F. B.
Date:
1878
Catalogue details

Licence: Public Domain Mark

Credit: Fibrin, its origin and development in the animal organism, and its relation to life, health, longevity, and disease / by John Goodman. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    by electric agency, greatly increased. Exp. 112.—The change to dense and opaque white was again effected in about half a minute. With older ov. albumen there is usually an increase in the amount of gas eliminated. Here we had a globule of albumen immersed in water midway between the poles, which was found to be a great advantage. In this experiment I per- ceived a dense, dark brown ring of fibrin forming around each bubble of gas, which we have preserved, and which can now be seen in the specimen. In fifteen minutes fibrinous rods were seen shooting forth like the fingers of a human hand (one of the most beautiful exhibitions I ever witnessed), towards the neg. pole, or in the lines of current. All these experiments, together with 113 and 115, in which, apparently, thousands of ovoid corpuscles made their appear- ance, many of which were attracted in beautiful lines, and formed rods—and many of them can still be seen in the speci- men—resulted in the formation of perfectly formed fibrin, without scarcely a vestige of unchanged albumen being left. Dr. Miller declares (p. 808) that, when fibrin is treated with acetic acid under the microscope, it is found to consist of two portions, one of which is granular and soluble in acetic acid, while the other is fibrinous and insoluble. This we found to be a graphic description of what took place with fibrin ab albumen. EPITOME OF EXPERIMENTS. I.—Solution. Exp. 9 and 69.—Fibrin ab albumen dissolved in 3 min. in liq. potass®. Exp. 66.—Bloocl fibrin was completely dissolved in twelve hours, whilst ov. albumen required more than twenty-four hours to effect its solution without heat. Here this substance ivas much more dissimilar to albumen than even blood fibrin itself. Exp. 52.—In strong hydro-chloric acid, fibrin ab albumen and blood fibrin both dissolved in txoenty-four hours, whilst ov. albu- men was not completely dissolved in sixteen days. II.—Frecipitated Solutions. In solution in acids precipitated by alkalies—and in alkalies precipitated by acids—this substance always manifested the same