Recent advances in the physiology of digestion.

  • Starling, Ernest Henry, 1866-1927.
Date:
1906
Catalogue details

Licence: In copyright

Credit: Recent advances in the physiology of digestion. Source: Wellcome Collection.

Provider: This material has been provided by Royal College of Physicians, London. The original may be consulted at Royal College of Physicians, London.

    96/176 (page 80)
    LECTUEE V. PANCREATIC SECRETION. The fluid chyme on entering the duodenum, the first jDart -of the small intestine, is subject at once to the influence of the :secretions of three different sets of glands, namely: (1) The intestinal glands, including those characteristic of the duodenum named Brunner's glands ; (2) The pancreas ; (3) The liver. The ducts of the two latter in many animals have a common opening into the duodenum, and in every case there is a ^o-operation between all three juices for the production of the intestinal digestive fluid. In discussing the mechanism of secretion of these juices, it will be more convenient to take .each kind of gland separately. The pancreas resembles the salivary glands, in that it is .comjposed of a mass of tubules, which pour their secretions into ,a common duct opening into the duodenum. It is therefore .easy to establish a temporary pancreatic fistula, by isolating the duct just before it joins the intestine, and inserting ,a small tube or cannula into it. A permanent fistula of the pancreas can be also established without difficulty. Indeed this operation is one of the earliest in the history of experi- mental physiology. De Graaf in his paper De Succo pancreatico, published in 1677, describes a method for the formation of a pancreatic fistula, and gives a figure of an animal in which both salivary and pancreatic fistulae had been established. The juice in each case was collected in small glass vessels tied to the tubes which had been