Reports of the trypanosomiasis expedition to the Congo, 1903-1904, of the Liverpool School of Tropical Medicine and Medical Parasitology / by J. Everett Dutton, John L. Todd and Cuthbert Christy / with a comparison of the trypanosomes of Uganda and the Congo Free State / by H. Wolferstan Thomas and Stanley F. Linton.

  • Dutton, Joseph Everett, 1876-1905.
Date:
1904
Catalogue details

Licence: Public Domain Mark

Credit: Reports of the trypanosomiasis expedition to the Congo, 1903-1904, of the Liverpool School of Tropical Medicine and Medical Parasitology / by J. Everett Dutton, John L. Todd and Cuthbert Christy / with a comparison of the trypanosomes of Uganda and the Congo Free State / by H. Wolferstan Thomas and Stanley F. Linton. Source: Wellcome Collection.

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    Case VI Sleeping Sickness (September 30, 1903).—N’Bela, male, aged 24, agricultural labourer. A Mongo man. Patient never saw sleeping sickness befére coming to Boma. Had lived in Boma for nearly three years. lness commenced in July of this year. Admitted to hospital, August 1, 1903. When the patient was seen (September 30) somnolence was already a marked feature of his condition. This symptom steadily became more marked as emaciation increased. When we left Boma (October 27) the patient was comatose, and death had been expected at any time during the preceding week. General Condition.—FPatient is thin and very weak. Questions are answered rationally, but only after a long interval. He displays a somnolent indifference to everything about him, and only by constant shaking can drowsiness be dispelled for a period long enough to permit him to speak. Physical Examination—Nervous system; co-ordination imperfect. Sense of weight good. Knee-jerks and superficial reflexes were obtainable, and showed no abnormality. Eyes reacted to light and to accommodation. Thoracic and abdominal examination showed nothing worthy of note. Lymphatic glands were all enlarged, hard, and freely movable. There was no haemorrhage into mucous membranes. Slight icterus of the conjunctiva was seen. The accompanying chart indicates-the course of the temperature in this case, and shows the results of the examinations for parasites. Trypanosomes were seen in both cerebro-spinal fluid and peripheral blood. On October 9, 35 c.cm. of slightly clouded, colourless cerebro-spinal fluid were taken by lumbar puncture. No red cells were seen in the fairly profuse deposit formed by centrifuging. This precipitate contained a fair number of trypanosomes, many monuclear cells of large size, and numerous polymorphonuclear leucocytes. ExperRIMENTAL INOCULATION The following animals have been inoculated from this case. The material inoculated was in each case demonstrated to contain living trypanosomes. ANIMALS INOCULATED FROM Case 6 October 7. White mouse (Experiment 16) inoculated subcutaneously with 1 c.cm. cerebro-spinal fluid ; infected October 25. October 7. White mouse (Experiment 17) inoculated subcutaneously with I c.cm. cerebro-spinal fluid ; never infected. 7 September 30. White rat (Experiment 5) inoculated subcutaneously with 5 c.cm. blood ; never infected. September 30. White rat (Experiment 6) inoculated intraperitoneally with 1 c.cm. blood ; never infected.