An investigation of an outbreak of cow-pox in Wiltshire : with a comparative account of some previous outbreaks in England, Germany, and France / by Edgar Crookshank.

  • Crookshank, Edgar M. (Edgar March), 1858-1928.
Date:
1888
Catalogue details

Licence: Public Domain Mark

Credit: An investigation of an outbreak of cow-pox in Wiltshire : with a comparative account of some previous outbreaks in England, Germany, and France / by Edgar Crookshank. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

    19/38
    put on the stretch by an assistant, and a number of scratches and cross-scratches were made, as in the ordinary process of vaccina- tion of infants, as superficially as possible, to avoid haemorrhage. The following are the details of the results which were ob- tained : First Series of Retro-vaccinated Calves. Calf 1, a small red calf, was vaccinated in six places. Next day a little dried serum had collected at the points of inoculation. The scratches were slightly reddened. The serum rubbed off in the course of a day or two, and there was no result from the retro- vaccination. Calf 2, a large red calf, was inoculated in six places. On the third day each place was promising. On the fourth day, Friday, December 9th, each place was tumid, reddened, and vesiculating. Temperature chart of retro-vaccinated calf (No. 2, red calf). The results were shown to Professors Brown and Axe and to Dr. Cumow. On the following day, these appearances were more marked; the areola had considerably increased. There was infil- tration extending around the inoculated spot for a distance of half an inch, and the discharge from the vesicle was turbid. On Mon- day, the 12th, brown crusts had formed, and, on pressure, pus ap- peared at the edges from underneath the crusts. The temperature of this animal is shown in Chart 1. Calf 3 was a small red calf. This calf was vaccinated in six places. No result followed the vaccination except topical irrita- tion. Calf 4, a blue-roan calf, was suffering from a severe attack of ringworm, consisting of thick eczematous-looking crusts on the side of the face and neck, along the back, and especially at the root of the tail. Similar results to those in Calf 2 occurred in all