Find thousands of books, manuscripts, visual materials and unpublished archives from our collections, many of them with free online access.

Nesidioblastosis in the neonatal pancreas

  • Anne Clark, University of Oxford
  • Digital Images
  • Online

Available online

view Nesidioblastosis in the neonatal pancreas

Licence

Attribution 4.0 International (CC BY 4.0)
You can use this work for any purpose, including commercial uses, without restriction under copyright law. You should also provide attribution to the original work, source and licence.
Creative Commons Attribution (CC BY 4.0) terms and conditions https://creativecommons.org/licenses/by/4.0
Credit: Nesidioblastosis in the neonatal pancreas. Anne Clark, University of Oxford. Attribution 4.0 International (CC BY 4.0)

Selected images from this work


About this work

Description

A photomicrograph of a stained section through a neonatal pancreas, showing nesidioblastosis. Nuclei are stained blue. This is a rare disease caused by excessive proliferation of islet cells derived from ductular epithelium (ductal stem cells) in the foetus, seen here as the layer of densely staining cells lining the pale triangular ductal area centre bottom of image. The brown-stained cells are neogenic beta-cells. The disease causes hypersecretion of insulin in the neonate, leading to severe persistent profound hypoglycaemia. The pancreas itself usually appears normal on imaging.


Permanent link