Adrenal tumor of vagina secondary to malignant hypernephroma of the kidney / by Alban Doran.

  • Doran, Alban H. G. (Alban Henry Griffiths), 1849-1927.
Date:
1907
Catalogue details

Licence: In copyright

Credit: Adrenal tumor of vagina secondary to malignant hypernephroma of the kidney / by Alban Doran. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    THE MEDICAL BRIEF J. J. LAWRENCE, A. M., M. D., EDITOR AND PROPRIETOR, NINTH AND OLIVE STREETS, ST. LOUIS, MO. NEW YORK OFFICE, ASTOR OOURT BLDQ. FOREIGN OFFICE! AUOKLANO HOUSE. BASINOHALL AVE., LON DON,E.O.,ENG. Vol. XXXV. December, 1907. No. 12 SUBSCBIPTION BATE3—INVAEIABLY IN ADVANCE. United States and Mexico, - - - per annum, $1.00 Foreign (Postal Union), - - - - “ 7s. 6d. These rates include postage. Advertising rates sent on application. All subscriptions will be discontinued at expiration unless renewed. The Medical Brief will not be sent unless paid for in advance. One Dollar per year in advance. Write only on one side of the paper. See how short and plain you can write. Write articles intended for publication, and matter for editor, on separate pieces of paper. Articles sent for publication in the Medical Brief must not contain more than seven hundred words. Short, practical, brief items always wanted. The Medical Brief is mailed on the first of each month. I f a number fails to reach you we will supply it, provided we are notified within a month. JPafThe Editor is not responsible for the articles of contributors. The MEDICAL BRIEF aims to publish articles on both sides of a question. The MEDICAL BRIEF has the largest paid circulation of any medical journal published anywhere. [Written for the Mkdical Brief.] Adrenal Tumor of Vagina Second- ary to Malignant Hyperne- phroma of the Kidney. BY ALBAN DOBAN, F. It., C. S., Surgeon to the Samaritan Free Hospital; Past President of the Obstetrical Society of London. London, England. Dwelling as much as possible on mat- ters of clinical interest, and avoiding deep pathological subtleties, I will relate a re- markable case in my own practice where a malignant tumor developed in the va- gina of a middle-aged woman, subject to enlarged kidney. I removed the kidney, and it was afterwards found that the renal growth was a hyperhephroma, a malignant tumor originating* iii; £Mlrenal- tissue in that organ, while the vaginal growth was not a coincident primary sar- coma, but a secondary adrenal tumor. A very similar case, as I will explain, was under observation in London at the same time as my own. My patient was a very sallow-complex- ioned married woman, aged forty, who called in her doctor on account of an at- tack of shivering, sweating and fever, early last autumn. A tumor was detected in the vagina, a racemose body attached by a well-defined pedicle to the lower part of the anterior vaginal wall. There were also three sessile growths in the posterior wall, one being jugulated. A small, mov- able tumor occupied the right iliac fossa. The lobules of the pedunculated growth were shed from time to time, and I sent them to Mr. Shattock, of the Royal Col- lege of Surgeons, and to my colleague. Dr. Cathbert Lockyer for examination. In November, 1906, I removed the abdominal tumor. It was a typical malignant ad- renal growth in the lower part of the right kidney, which had become twisted in its pedicle so that the tumor lay up- permost, touching the liver, whilst the upper pole of the kidney lay downwards, rotated on the lower part of the lum- bar spine. As there was considerable shock, I postponed the removal of the original growths. The patient survived the nephrectomy three months, after de- clining to allow a second operation for the removal of the polypus and the ses- sile tumors in the vagina. Until her death, lobules continued to come away from the vagina, and symptoms of pulmonory com- plication were observed. At the post-mor- tem secondary deposits were found in the liver, lungs and intestine Under the mi- croscope it was found that the vaginal poly- pus and the omental and visceral de posits were histologically identical with the renal tumor, a malignant adrenal growth, which was declared by the path- ologists above mentioned to be an adrenal carcinoma, and not sarcomatous. Just before I brought forward my case at a meeting of the Obstetrical So- ciety of London, I mentioned it to Dr. Beckett-Avery, who, to my surprise, in- formed me that he had recently been in-