Collagen fibril forming in vitro

  • Rob Young
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Collagen fibril forming in vitro. Rob Young. Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Source: Wellcome Collection.

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A collagen fibril forming in a test tube from a solution of purified collagen protein. The new molecules arrange themselves at the tip of the fibril in a very organised way. The result of the precise alignment of the individual collagen molecules is the typical pattern of light and dark bands across the fibril. This self-assembly is a naturally occurring process like those exploited in various forms of nanotechnology. Collagen forms the basis of a lot of the connective tissue in the body and is becoming increasingly popular as a cosmetic treatment for filling out wrinkles, lips and old scars. Biomedical Image Awards 2006.

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