On intermittent hæmaturia : with remarks upon its pathology and treatment / by George Harley, M.D.

  • Harley, George, 1829-1896.
Date:
1865
Catalogue details

Licence: Public Domain Mark

Credit: On intermittent hæmaturia : with remarks upon its pathology and treatment / by George Harley, M.D. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

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    first two years lie was still liable to oecasioiial outbursts of his old cuemy. On one occasion, Avhile consulting me re- garding his case, he mentioned what he considered to be a very peculiar symptom, namely, that he occasionally suddenly l)assed five or six ounces of urine of a dark red or chocolate colour, a symptom which would recur once in twenty-four hours during two or three days, and then as suddenly disap- pear. Never having before met with such a ease, I requested him to send to me, on the next occasion, a specimen of the fluid. In the succeeding November (1861) I received from this gentleman three samples of urine—one passed at 8 a.m., which was clear, pale, of a specific gravity of 1025, of an acid reaction, depositing no lithates, and containing no albumen, being, in fact, normal in every respect. Another quantity, passed at 2 p.m. of the same day, of a dark chocolate-brown colour, opaque, turbid, having a specific gravity of 1033, of an acid reaction, depositing lithates, containing a large quan- tity of albumen, some sugar, and a large excess of urea (3*6 l)er cent.). The deposit from this specimen of urine, when ex- amined with the microscope was found to contain nucleated epithelium (Fig. a, 1), some granular cells (Fig. a. 2), and a large quantity of free granules of a brownish-red hjematin colour, scattered among Avhich were a considerable number of renal tube-casts. The tube-casts presented one or two remarkable peculiarities, namely, that the majority of them were short and broad, and filled ehokefull with brown pig- ment, as represented at Fig. a, 3. Besides these there were a small number of fine, long, pale tube-casts, with only a few granules of dark pigment distributed in them (Fig. a, 4); these looked not at all unlike the renal tubes emptied of their epithelium obtained by scraping a section of fresh kidney. No blood-corpuscles were to be found in this speci- men of urine. The third sample of urine sent by the gentle- man in question was passed in the evening of the same day, and presented a striking contrast to that just described. It was normal in colour, contained no albumen, deposited a small quantity of ordinary coloured lithates, among which were neither tube-casts nor granular cells. The specific