Macrodactyly, and some other forms of congenital overgrowth, and their relation to tumours / by Sir George Murray Humphry.

  • Humphry, George Murray, Sir, 1820-1896.
Date:
1891
Catalogue details

Licence: Public Domain Mark

Credit: Macrodactyly, and some other forms of congenital overgrowth, and their relation to tumours / by Sir George Murray Humphry. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    family are reported to have been deformed in a similar manner. (No. 11.) The case of a girl, aged five, by Mr. Power, of Dublin,^ with the middle finger of the right hand much, and the index and ring finger somewhat enlarged, particularly the ring finger, which was divaricated from the middle in consequence of its abnormal growth. (No. 12.) Dr. John Reid^ gives the case of a boy, aged thirteen, in whom there was increased nutrition of the thumb and first finger of the left hand. The enlargement was associated with enlargement of the radial artery and elevation of temperature, was observed at birth, and continued to in- crease. In this paper Dr. Reid also describes the case (No. 13) of a lad, aged fifteen, with congenital hypertrophy of the whole of the left upper limb including the scapula ; and (No. 14) that of a girl, aged two, with congenital hypertrophy of the middle toe which equalled in bulk all the remaining four toes, the phalanges and metatarsal bone being of great size. Busch, in an excellent article,® relates two cases. One (No. 15) a man, aged twenty, with congenital hypertrophy and deformity of the three inner toes, which were much over-extended, and the adjacent part of the sole of the right foot, the growth proceeding out of proportion to the rest of the body and advancing along the sole (resembling, in short. No. 6). Pirogoff’s amputation was performed. The phalanges, metatarsals, and inner tarsal bones were enlarged, especially at their articular ends ; and these were deformed, tuberculated, and in some instances anky- losed; the ligaments thick, and the synovial fringes pro- nounced ; much and disproportionate increase of fatty tissue, causing deformity and bulk; the arteries and nerves unaltered; the dorsal veins in part greatly thickened by fibrous formation in concentric sheets in their walls without increase of lumen; two outer toes quite free from hypertrophic change; the small muscles ' ‘ Dublin Journal of Med. Science,’ xvii, 244. ’ ‘ London and Edin. Monthly .Tournnl of Med. Sc.,’ 1843, p. 198. 3 Langenbcck’s ‘ Archiv fiir klinische Cbirurgie,’ vii, 174, and pi. vi.