Carcinoma mammae in the mouse / by E.F. Bashford and J.A. Murray.

  • Bashford, Ernest Francis, 1873-
Date:
[1907]
Catalogue details

Licence: In copyright

Credit: Carcinoma mammae in the mouse / by E.F. Bashford and J.A. Murray. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    c CARCINOMA MAMMAE IN THE MOUSE* By E. F. BASHFORD, M.D.Edin., GENERAL SUPERINTENDENT OF RESEARCH AND DIRECTOR OF THE LABORATORY OF THE IMPERIAL CANCER RESEARCH FUND ; AND J. A. MURRAY, M.B., B.Sc.Edin., ASSISTANT, IMPERIAL CANCER RESEARCH FUND. From the outset o£ the investigations of the Imperial Cancer Research Fund, in October 1902, every effort has been made to give effect to the desire of the Executive Committee to develop the experimental aspects of the study of cancer. In directing the attention of other investigators to the experimental study of cancer we pointed out that, in the first place, it was essential to be sure we were dealing with malignant new growths comparable to those of the human subject1. We have carefully satisfied ourselves of the carcinomatous nature of the growths on which our experimental observations have been based, but have purposely avoided burdening our papers with details of descriptive pathology2. We have been equally careful in regard to sarcomata and have even excluded growths which other observers have claimed we should have included— e. g., certain venereal tumours of dogs. As regards the latter, we may say at once that we believe the course of events during the past four years has justified our caution. The high degree of natural infectivity, the constancy of the site of occurrence—viz., the genital organs—and the ease of artificial infection of healthy animals, as well as the processes responsible for infection, showed that those tumours differ from other sarcomata which they resemble histologically. We concluded that the tumours were an infective venereal disease of dogs, perhaps comparable to syphilis of man3, or better to granuloma pudendi. Sticker4, Ewing * The superior figures occurring throughout the article refer to the bibliography at the end. a