Hyperkeratosis of the heel. Hyperkeratosis describes a thickening of the outer layer of the skin caused by abnormally increased amounts of the protein keratin which normally functions to protect the skin.

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Hyperkeratosis of the heel. Hyperkeratosis describes a thickening of the outer layer of the skin caused by abnormally increased amounts of the protein keratin which normally functions to protect the skin. Geraldine Thompson. Attribution 4.0 International (CC BY 4.0). Source: Wellcome Collection.