Volume 2

Histologische und histopathologische Arbeiten über die Grosshirnrinde : mit besonderer Berücksichtigung der pathologischen Anatomie der Geisteskrankheiten / herausgegeben von Franz Nissl.

Date:
1904-1913
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Histologische und histopathologische Arbeiten über die Grosshirnrinde : mit besonderer Berücksichtigung der pathologischen Anatomie der Geisteskrankheiten / herausgegeben von Franz Nissl. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    promiscuously, others beginning to arrange themselves in ranks and penetrating the platelet on all sides; and they will he recognised as identical with the fibroblasts whose development from the pial connective tissue has been traced above, (v. Fig. 4. PI. II.) Does the comparison still hold good in the case of the gitter cells? Numerous pictures of the cortical vascular elements at 48 hours after operation show conclusively that the above described metamorphosis of pial connective tissue cells into free gitter cells is exactly duplicated at a little later period in the endothelial elements of the cortical capillaries. Often enough one finds along the proliferating capillary walls instead of two daughter endo- thelial cells or a fresh endothelial bud branching off from its sister element in the wall, a newly developed gitter cell occupying this position whose nucleus shows no essential differences in structure from that of the adjacent endothelial cell and whose cell body differs from the latter only in appearing a little more circumscribed and its meshes a little more distinct and vacuole-like. Often the gitter cell lies close to the vessel wall at its place of origin while the endothelial sprout takes at once a diverging course, but the opposite relations obtain perhaps nearly as often. Fig. 12. PI. II. shows a gitter cell springing from a capillary wall (a) and growing away from the vessel into the tissue but still connected by a stem with its endothelial origin. Again is to be noticed the striking resemblance of the gitter cell (b) to the adjacent endothelial cell (c) from which it has doubtless just been separated. At another place (Fig. 5. PI. II) the identity of origin of the offshooting anlagen (b) and the closely similar gitter cell (c) still lying against the vessel wall, is again clearly illustrated. That an endothelial cell should divide and give rise at one time to a fibro- blast which may become a fixed and permanent vascular element, at another, to a gitter cell which will separate itself entirely from the vessel, subserve a function essentially different from that of the fibroblast, and succumb after a relatively short period to degenerative changes, we put down simply as an observed fact, without in the least being able to understand the determining causes. Moreover forms not infrequently occur in which it is im- possible to say with which cell type we have to do. Position and form are by no means distinguishing features—both gitter cells and fibroblasts may assume round, irregular or elongated forms, and may lie in close relation with the vessel wall or free among the Histologische und histopathologische Arbeiten. 2. Band. 3