Experimental researches into a new excretory function of the liver : consisting in the removal of cholesterine from the blood, and its discharge from the body in the form of stercorine (the seroline of Boudet) / by Austin Flint, Jr. ; illustrated by three plates containing fifteen figures.

  • Flint, Austin, 1836-1915.
Date:
1862
Catalogue details

Licence: Public Domain Mark

Credit: Experimental researches into a new excretory function of the liver : consisting in the removal of cholesterine from the blood, and its discharge from the body in the form of stercorine (the seroline of Boudet) / by Austin Flint, Jr. ; illustrated by three plates containing fifteen figures. Source: Wellcome Collection.

Provider: This material has been provided by the National Library of Medicine (U.S.), through the Medical Heritage Library. The original may be consulted at the National Library of Medicine (U.S.)

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    [Extracted from The American Journal of the Medical Sciences for October, 1862.] EXPERIMENTAL RESEARCHES NEW EXCRETORY FUNCTION OE THE LIVER; CONSISTING IN THE REMOVAL OF CHOLESTERINE FROM THE BLOOD, AND ITS DISCHARGE FROM THE BODY IN THE FORM OF STERCORINE. (THE SEROLINE OF BODDET.) By AUSTIN FLINT, Jr., M. D., ^ ' / ^ ^ PROFESSOR OF PHYSIOLOGY AND MICROSCOPY IN THE BELLEVUE HOSPITAL MEDICAL COLLEGE, NEW YORK; MICROSCOPIST TO BELLEVUE HOSPITAL. ILLUSTRATED BY THREE PLATES CONTAINING FIFTEEN FIGURES. La Cholesterine du sang est elle un de ces produits destines d Ure expuhts de V 6conomie, et, par consequent, depourvus d'action immediate sur Viconomie elle mhne? Sa destination est tout d fait mconnue. Trait6 de Physiologie, par F. A. Longet. Paris, 1861. Tome i. p. 488. This sentence, which is taken from the most elaborate treatise on phy- siology in any language, published at the centre of physiological science, in 1861, expresses the state of our knowledge with regard to the function of cholesterine. Cholesterine was discovered in 1782, by Poulletier de 1% Salle, in biliary calculi, and was detected upwards of thirty years ago in the blood by Denis; but since then, with the exception of researches of a purely chemical nature into its properties, our knowledge with regard to it has not advanced. Its chemical history even, is far from perfect; while its physiological history is unknown. In 1833 Boudet discovered a substance in the blood which he called Seroline; a principle having many characters in common with cholesterine, but heretofore interesting merely as a curious proximate principle, found in excessively minute quantities in the serum of the blood only (whence its name); too minute, indeed, for ultimate analysis. Its function was as obscure as that of cholesterine. In examin- ing the literature of these two substances, we find that cholesterine is fre- quently not treated of in systematic works on physiology. Seroline is sel- 1