On the mode of communication of cholera / by John Snow.

  • John Snow
Date:
1855
Catalogue details

Licence: Public Domain Mark

Credit: On the mode of communication of cholera / by John Snow. Source: Wellcome Collection.

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    ease, whenever an examination of the body has taken place after death. In all the cases of cholera that I have attended, the loss of fluid from the stomach and bowels has been sufficient to account for the collapse, when the previous condition of the patient was taken into account, together with the suddenness of the loss, and the circum- stance that the process of absorption appears to be sus- pended. The symptoms which follow the affection of the aliment- ary canal in cholera are exactly those which this affection is adequate, and, indeed, could not fail to produce. The analyses which have been made of the blood of cholera patients, show that the watery fluid effused into the stomach and boAvels is not replaced by absorption, or is replaced only to a small extent. The analyses of Dr. O’Shaugh- nessy and others, during the cholera of 1831-32, show that the amount of water in the blood was very much diminished in proportion to the solid constituents, and that the salts of the blood were also diminished. The analyses of Dr. Garrod and Dr. Parkes, in the spring of 1849, were more numerous and exact.* The amount of water in the blood of healthy persons is on the average 785 parts in 1000; whereas, in the average of the analyses performed by Drs. Garrod and Parkes, it was only 733 parts, while the amount of solid constituents of the blood, relatively to the water, was increased from 215 — the healthy standard—to 267. The globules, together' with the albumen and other organic constituents of the serum, amount in the healthy state to 208 parts in 1000, while in the blood of cholera patients they amounted to 256 parts. The saline constituents in 1000 parts of blood are some- what increased, on account of the great diminution of water ; but, when estimated in relation to the other solid