On the relation of cow-pox and horse-pox to small-pox. : A thesis read for the degree of M.D. Cantab / by Robert Cory.

  • Cory, Robert.
Date:
1885
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Licence: Public Domain Mark

Credit: On the relation of cow-pox and horse-pox to small-pox. : A thesis read for the degree of M.D. Cantab / by Robert Cory. Source: Wellcome Collection.

Provider: This material has been provided by London School of Hygiene & Tropical Medicine Library & Archives Service. The original may be consulted at London School of Hygiene & Tropical Medicine Library & Archives Service.

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    His other conclusions refer to an artificial method of pro- ducing this modification in small-pox virus without the aid of the cow. This he thought he did by preserving small- pox virus for ten days between two pieces of glass^ and then diluting it with milk and using* this mixture for vaccinating children. The lymph obtained from the resulting vesicles he again kept and diluted with milk as before. After ten generations the lymph had become modified, and could be used without the addition of milk.^ Mr. Ceely, in 1839, also succeeded in inoculating cows with small-pox, and found that the resulting lymph caused a disease identical with vaccinia. His experiments are published in the 8th vol. of the ' Transactions of the Pro- vincial Medical and Surgical Association,' and also in a separate work, entitled ' Observations on the Variolas Vac- cinas,' 1840, Worcester. In a note, p. 140, of the latter, which I quote to show that his experiments were independent of Dr. Theile's, he says : But I am gratified to learn that since the announcement of those [experiments] which I have just detailed, intelligence has been received of the success of Dr. Basil Tlieile, of Kasau, in Russia, in similar experi- ments. He also, on the same page, states that when he wrote, more than 20U0 subjects had been vaccinated with his variola vaccine lymph. About this time also Dr. Reiter, of Munich, succeeded. He had failed previously, but having' adopted the method of inoculation practised by Dr. Theile, he succeeded. In IBlO, Mr. Badcock, then a chemist in Brighton, succeeded on his first attempt, and afterwards succeeded some thirty or forty times ; nevertheless his successes only amounted to about 7 per cent, of his trials.^ Some of the lymph thus obtained by Mr. Badcock, so he in- forms me, furnished the stock which was used at the High- gate small-pox and vaccination hospital for some fifteen years or more by Mr. Marson. Dr. Vy,' of Elburg, in 18G7, also succeeded, and used the lymph for vaccination. ' Henke's ' Zcitschrift fiir die Staatsarzneikuiid,' 1839. ' 'Detail of Experiments proving the Identity of Cow-pox and Suiall-pox,' Brighton, 1845. ' Bulletin de I'Acad. de Med.,' t. xxxi, p. 430.