Inborn errors of metabolism / by Archibald E. Garrod.

  • Garrod, Archibald E. (Archibald Edward), Sir, 1857-1936.
Date:
1909
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Inborn errors of metabolism / by Archibald E. Garrod. Source: Wellcome Collection.

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    CHAPTER I The Inborn Errors of Metabolism The differences of structure and form which serve to distinguish the various genera and species of animals and plants are among the most obvious facts of nature. For their detection no scientific training is needed, seeing that they cannot escape the notice of even the least cultivated intelligence. Yet with the growth of knowledge we have learned to recognize the uniformity which underlies this so apparent diversity, and the genetic relationship of form to form. With regard to the chemical com position of the tissues of living organisms, and the metabolic processes by which those tissues are built up and broken down, the advance has been in the opposite direction, for the progress of chem ical physiology is teaching us that behind a super ficial uniformity there exists a diversity which is no less real than that of structure, although it is far less obvious. The differences of ultimate composition and crystalline form which distinguish the haemoglobins of animals of distinct genera have long been known. That the fats of animals are not alike in composition is 1 1