A note on the histology of a case of myelomatosis (multiple myeloma) with Bence-Jones protein in the urine (myelopathic albumosuria) / by F. Parkes Weber and J.C.G. Ledingham.

  • Weber, Frederick Parkes, 1863-1962.
Date:
1909
Catalogue details

Licence: In copyright

Credit: A note on the histology of a case of myelomatosis (multiple myeloma) with Bence-Jones protein in the urine (myelopathic albumosuria) / by F. Parkes Weber and J.C.G. Ledingham. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    features of the growth after describing the results of macroscopic and microscopic examination of the viscera. The heart (weight 9^ oz.) showed nothing abnormal. The aorta, as much of it as was examined, showed no excessive atheroma, excepting some calcification quite at its commencement, close to the aortic valves. There were a few old pleuritic adhesions. There was hypostatic congestion of the bases of the lungs, and the hardened condition of the left lower lobe suggested the presence of actual pneumonia. Microscopic examination of this part of the lung proved that there was pneumonia and that the pulmonary alveoli were Fig. i. Microphotograph showing the pneumonia. (Magnification, 500.) typically infiltrated with pus-cells (fig. 1). Examination of blood-films from the blood in the heart gave the following differential count (J. C. G. Ledingham) of white cells: small lymphocytes T2 per cent. ; large lymphocytes 19 per cent. ; large mononuclears and transitionals 0'6 per cent.; polymorphonuclears 77’3 per cent. ; eosinophiles 0 ; myelocytes T8 per cent. A good many of the polymorphonuclears appeared immature, approaching the myelocyte type. No plasma-cells could be distinguished. No nucleated red cells were seen. No changes were observed in the red cells.