Progressive muscular dystrophy : comparisons of some of the varieties with each other, and with progressive muscular atrophy / by J.H. Crocker.

  • Crocker, J. H (John Hedley)
Date:
1894
Catalogue details

Licence: Public Domain Mark

Credit: Progressive muscular dystrophy : comparisons of some of the varieties with each other, and with progressive muscular atrophy / by J.H. Crocker. Source: Wellcome Collection.

Provider: This material has been provided by The University of Leeds Library. The original may be consulted at The University of Leeds Library.

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    diseases are separable. Speaking generally, Simple Idiopathic Muscular Atrophy appears later than Pseudohypertrophic, and the varieties of Idiopathic cases appear at different ages. Accord- ing to Duchenne, the type where the face is implicated appears early, as a rule, from 5 to 7. Erb's Juvenile most commonly about puberty, etc. If, as is admitted, these varieties of Idiopathic cases appear at different ages, then it is possible on that line of argument to admit Pseudo-hypertrophic Muscular Paralysis in the same list. There are many exceptions to the conclusions mentioned above, as for instance, Mrs P , aged 54, has only a few muscles of the face affected. Case 9, an example of Erb's Juvenile, began at 8. Landouzy and Dejerine have reported a case beginning at 3 years of age ; on the other hand, Gowers mentions a case as late as 60. Barsickow gives a list of 17 cases where the ages were known at which the disease commenced :—One appeared at 12, four between 15 and 20, seven between 20 and 30, three between 30 and 40, and two after 40. A woman aged 52, began at 30, but her son began at 3 years of age.17 In the article before mentioned, Erb gives the details of 23 cases of his Juvenile form ; the following list shows the ages at which the disease was recognised, possibly a skilled eye would have noticed them much earlier in some cases, as it is only when there is a decided loss of use that advice is sought as a rule. Males : 34, 20, 13, 17, 18, 6, 16, 18, 18, (Initial letter only, not certain as to sex) 40, 42, 16, 22, 12, 10—14 (brothers.) Infancy— Infancy (brothers) 14, 20, 10. Females : 16, 10. Pseudo-hypevtvophie cases begin earlier as a rule, often the first symptoms are noticeable when the child ought to begin to walk. According to Ross, most cases begin from 5 to 13 years of age, but some are recorded where it began in adults. Ross,18 had a case in which the patient began at 10 and was alive at 47. Gowers,19 referring to the ages of 123 males and 16 females gives the following : (17) Diseases of Nervous System, Gowers' Vol. i, p. 522. (18) Diseases of Nervous System. Ross,—1883, Vol. 1, p. 993. (19) Pseudo-hypertrophic Muscular Paralysis—Gowers, 1879, p. 36.