Further observations on the internal use of the hydro-cyanic (prussic) acid : in pulmonary complaints; chronic catarrhs; spasmodic coughs; asthma; hooping-cough; and some other diseases. With full directions for the preparation and administration of that medicine / by A.B. Granville.

  • Augustus Granville
Date:
1819
Catalogue details

Licence: Public Domain Mark

Credit: Further observations on the internal use of the hydro-cyanic (prussic) acid : in pulmonary complaints; chronic catarrhs; spasmodic coughs; asthma; hooping-cough; and some other diseases. With full directions for the preparation and administration of that medicine / by A.B. Granville. Source: Wellcome Collection.

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    of instances, with variable success; but, the benefit it has produced is amply sufficient to authorize me to add my testimony in fa¬ vour of its value, as an important addition to the list of direct sedatives. The Prussic Acid, when taken into the stomach, produces its action on the circu¬ lating system, evidently through the medium of the nerves, the energy of which it consi¬ derably lessens, and even altogether de¬ stroys when the dose is sufficiently strong* In no case have I remarked that any ex¬ citement precedes its sedative effect, a circumstance which distinguishes it from every other substance belonging to the class of narcotics. The opinion of Orfila* and some others, that it is rapidly absorbed and transmitted through the current of the circulation, and that its fatal effect, when given in a concentrated form, is more or less rapid in proportion to the activity of the circulation, is rendered questionable by the instantaneous manner in which it produces death, when exhibited undiluted in large * Vide Traits des Poisons, Tome seconde, premiere Par tie. p. 186. Fa t
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