Surgery : its theory and practice / by William Johnson Walsham.

  • Walsham, William Johnson, 1847-1903.
Date:
1890
Catalogue details

Licence: Public Domain Mark

Credit: Surgery : its theory and practice / by William Johnson Walsham. Source: Wellcome Collection.

    21/902 (page 5)
    from the multiplication of the original tissue elements. More recently it has been attributed to the aggregation of the escai^ed leucocj^tes, the tissue elements being believed to remain passive or to undergo degeneration ; whilst more recently still it has been ascribed in chief part to the proliferation of the connective-tissue and other cells m the inflamed area, the leucocytes being thought to play only a subordinate part and sooner or later to undergo disintegration or absorption. From whatever source these cells are derived, among them may soon be seen numerous delicate capillary loops, which liave been formed from the old capillaries in and around the in- flamed area. To this vascularized tissue the name of inflammatory new formation or granulation-tissue is given. When the cells and liquid escape on a free sur- face, the fibrin with the entangled cells forms a so-called false membrane. 2. Changes in the fixed elements of the tissues.—When the mesentery is examined after inflammation has existed a short time, the cells of the original tissue are found to be proliferating. The nuclei of the endotheHal cells divide, and the daughter cells thus produced lose their endothelial characters and become pear-shaped and larger than the escaped leucocytes surrounding them. The con- nective-tissue cells are beHeved to divide and proliferate m like manner. Thus, in the earlier stages of inflam- mation, two kinds of cells may be found—a number of small round cells, leucocytes, which have escaped from the vessels, and amongst them larger cells, which exhibit ama'boid movements on a warm stage, and are now looked upon as being derived in the way above mentioned from the original tissue cells. These large cells are believed by many recent pathologists to continue to divide and multiply, and to form in chief part the cells of the in- flammatory new formation or granulation tissue. They are calhxl fibro-blasts. The escaped leucocytes are sup- posed by the supporters of this view of the formation of granulation tissue, to undergo dogonoration and aljsor])- tion, or to take only a limited share in its ]iroduction. . TermiriMtiniis «f iiiflaviinutM,n.--^o have alroadv soen tjiat before coagulation ha,s taken jjlace and the tissues have become irreparably damaged, if the cause of tho mflammation ceases to act, the process may terminate and the part resume its noi-mal conditions, when resolution IS said to occur. Failing this, however, the following