The cerebral lesions in a case of complete acquired colour-blindness / by George Mackay and James Crauford Dunlop.

  • Mackay, George, 1861-1949.
Date:
[1899]
Catalogue details

Licence: Public Domain Mark

Credit: The cerebral lesions in a case of complete acquired colour-blindness / by George Mackay and James Crauford Dunlop. Source: Wellcome Collection.

Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)

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    To study how far the atrophy extended into the brain surface, three sections were made. One of these (B in fig. 3) was through the centre of the atrophic convolution, another (A) was anterior to that, the third (C) was posterior. These sections were stained both by Heller's method and by alum haematoxylin. Section B, that through the centre of the lesion, showed {vide fig. 5) the following points :— 1. A marked atrophy, both of grey and of white matter in a region localised as the temporo-occipital convolution. This convolution was apparently all destroyed with the exception of the association fibres at the inner side of the convolution. 2. No affection of the grey matter of the calcarine fissure. 3. An atrophy of the lower edge of the optic radiation. Section A, anterior to the one described {vide fig. 4), shows the same involvement of brain tissue as seen in section B, namely atrophy of temporo-occipital convolution, no involve- ment of calcarine fissure, and some involvement of lower edge of optic radiation. It, however, shows that at this level the atrophy of the optic radiation is slightly more extensive than that at the level of section B. Section C, posterior to B, shows the same atrophy of the occipito-temporal convolution {yide^^. 6). It also shows that both the grey and white matter of the calcarine fissure are unaffected, but as the optic radiation is at this level no longer a distinct structure, it does not appear whether it is affected or not. Left occipital lobe.^ The examination of the. left side of brain showed a lesion of the occipital lobe very similar to that found on the right sidcj with the exception that on inspection of the surface the atrophy was not so evident, there being no marked depression as on the right side, and no' distinctly shrivelled convolution ; it was, however, indicated by some pigmentation. The position of this , pigmentation was identified as the posterior end of the temporo-occipital con- volution. Sir William Turner kindly corroborated that localisa- tion. Two sections of the left- side of the brain were stained and examined, section D {vide fig. 7) being made at a plane corresponding as closely as possible to section B of the right side ; the other section, E {vide ^g. 8), was posterior to D, and intended to correspond with section C of the right side.