Vaccination, its natural history and pathology.

  • Copeman, S. Monckton (Sydney Monckton), 1862-
Date:
1899
Catalogue details

Licence: Public Domain Mark

Credit: Vaccination, its natural history and pathology. Source: Wellcome Collection.

Provider: This material has been provided by the Harvey Cushing/John Hay Whitney Medical Library at Yale University, through the Medical Heritage Library. The original may be consulted at the Harvey Cushing/John Hay Whitney Medical Library at Yale University.

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    overruled. For his own satisfaction, however, Klein endeavoured to vaccinate one of the cows which had shown some local reaction, but entirely without result, the animal apparently being immune. Of my own experiments the most successful series may briefly be described as follows :—With variolous lymph (contained in two capillary tubes) taken on 30th July 1892 from a vaccinated girl, aged sixteen years, at from the fifth to the sixth day of the eruption of discrete smallpox, I inoculated on nth August a cow-calf A, about six weeks old, by thirty-two linear incisions and two superficial scarified patches made on the abdomen. On 13th August (the third day) this calf presented nothing but a slight scab over the scarified patch. On 15th August (the fifth day) some of the incisions were somewhat red and elevated, more particularly at several definite points which tended to be vesicular. At this date, on the inner aspect of each thigh, and distant in each instance from incisions or scarifications, was a crop of shotty and incipiently vesicular pimples. On 17th August (the seventh day), having clamped three of the incisions, including those with the quasi - vesicular appearance, I removed the lymph with the crusts by scraping, and used the material for the inoculation on this date of calf B. The accessory incipient vesicles I left untouched. From first to last calf A never exhibited any appreciable rise of temperature or indisposition of any sort. On the ninth day the linear incisions, the cross scarifications, and the accessory vesicles of calf A were in their decadence, and in a few days more the