Vaccination, its natural history and pathology.

Sydney Copeman

Date:: 1899

Credit: Vaccination, its natural history and pathology. Source: Wellcome Collection.

Provider: This material has been provided by the Harvey Cushing/John Hay Whitney Medical Library at Yale University, through the Medical Heritage Library. The original may be consulted at the Harvey Cushing/John Hay Whitney Medical Library at Yale University.

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Lymph of equine origin—Origin of lymph used at the Govern- ment Animal Vaccine Establishment — Variola-vaccine lymph Pages 67-72 CHAPTER IV HISTOLOGY OF THE VACCINE VESICLE Cause of papular stage of vaccination—Description of vesicle— Action of leucocytes—Pustular stage—Gustav Mann's investiga- tions as to changes produced in skin of calf by vaccination— Chemistry and morphology of vaccine lymph 73-84 CHAPTER V BACTERIOLOGY Granules in vaccine lymph—Micro-organisms in—Specific micro- organism of—Action of glycerine on—Experiments with horse- pox lymph— Extraneous micro-organisms in vaccine lymph— Tubercle bacillus in—Variolation of bovine animals—Cultivation of micro-organisms of variola and vaccinia in artificial media— Protozoa S5-127 CHAPTER VI VARIOLA AND VACCINIA IN THE MONKEY Investigations as to efficiency of lymph stocks by variolation and vaccination of the monkey—Difference between variolation and vaccination of the monkey—Comparison of effects produced by human and by calf lymph—The variolous test . 128-133

Vaccination, its natural history and pathology.

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