Cancer as a metabolic disease : on the origin, management, and prevention of cancer / Thomas N. Seyfried.

  • Seyfried, Thomas N., 1946-
Date:
[2012]
  • Books

About this work

Description

The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.

Publication/Creation

Hoboken, New Jersey : Wiley, A John Wiley & Sons, Inc., Publication, [2012]

Physical description

xvi, 421 pages : illustrations (some color) ; 24 cm

Contributors

Bibliographic information

Includes bibliographical references and index.

Contents

Images of cancer -- Confusion surrounds the origin of cancer -- Cancer models -- Energetics of normal cells and cancer cells -- Respiratory dysfunction in cancer cells -- The Warburg dispute -- Is respiration normal in most cancer cells? -- Is mitochondrial glutamine fermentation the missing link in the metabolic theory of cancer? -- Genes, respiration, viruses, and cancer -- Respiratory insufficiency, the retrograde response, and the origin of cancer -- Mitochondria: the ultimate tumor suppressor -- Abnormalities in growth control, telomerase activity, apoptosis, and angiogenesis linked to mitochondrial dysfunction -- Metastasis -- Mitochondrial respiratory dysfunction and the extrachromosomal origin of cancer -- Nothing in cancer biology makes sense except in the light of evolution -- Cancer treatment strategies -- Metabolic management of cancer -- Patient implementation of metabolic therapies for cancer management -- Cancer prevention -- Case studies and personal experiences in using the ketogenic diet for cancer management.

Languages

Subjects

Where to find it

  • LocationStatus
    Medical Collection
    QZ202 2012S51c
    		Open shelves

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Identifiers

ISBN

  • 9780470584927
  • 0470584920