A method of standardising pituitary (infundibular) extracts / by H.H. Dale and P.P. Laidlaw.

  • Dale, Henry Hallett, 1875-1968.
Date:
1912
Catalogue details

Licence: In copyright

Credit: A method of standardising pituitary (infundibular) extracts / by H.H. Dale and P.P. Laidlaw. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    day. We have deliberately emphasized those sources of error which demand care and experience for their complete elimination. At the same time it should be made clear that the precautions mentioned above are only needed for the application of the method with a fineness of discrimination altogether beyond the range of Fig. 8. Comparison with the Standard (S) of a Nearly Equivalent Extract (X) At A, 0.0125 cc. X (abnormal effect of first dose); at B, 0.0125 cc. S; at C, 0.0125 cc. X; at D, 0.0125 cc. S. differences appreciable by other methods. In our experience a difference of activity which is only just appreciable by the blood- pressure method under the best conditions is at once obvious by the test on the uterus without any special care in controlling the regularity of the response. Such a case is shown in Fig. 5, which