Volume 3

Manual of pathological histology / by Cornil and Ranvier.

  • Cornil, V. (Victor), 1837-1908.
Date:
1882-1886
Catalogue details

Licence: Public Domain Mark

Credit: Manual of pathological histology / by Cornil and Ranvier. Source: Wellcome Collection.

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    central lumen. But they are not found at least in the early stages of cirrhosis, in the fibrous trabeculse which accompany the hepatic veins, for there are none in this situation normally. In certain cases, however, of chronic hypertrophic cirrhosis, networks of bile ducts may be seen in all the fibrous trabeculse, in those which are developed along the hepatic veins as well as those which accompany the portal veins. It is thus necessary to ask how and from what elements these canaliculi originate. It must first be noticed that these anastomotic canaliculi are not always of the same diameter : at the centre of a thick band of cirrhosis one or two wide-mouthed ducts may be found free or filled with detached cells derived from their epithelial lining ; the diameter of these ducts may vary from 20 to 60 yLt, which is equal or larger than that of the normal perilobular ducts (see/, fig. 145). Besides these, numerous smaller canaliculi are present which are recti- lineal or undulating, and form by their anastomoses elongated or polygonal meshes more or less regular. These canaliculi are completely lined with small cells, which are sometimes cubical, sometimes elongated and flattened in the Fig. 145.—Network of Bile Canaliculi situated in the new Connective Tissue of Cirrhosis. /, interlobular bile duct ; c, very small duct continuous with other canaliculi equally delicate, and containing cells placed end to end. These canaliculi lead into larger ducts, a, ft', a ; d, connective-tissue cell. Magnified 300 diameters. direction of the duct. The ducts are united together by very delicate branches, which also often contain a single row of cells