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Circadian rhythms : a subject collection from Cold Spring Harbor perspectives in biology / edited by Paolo Sassone-Corsi, University of California, Irvine, Michael W. Young, the Rockefeller University, Akhilesh B. Reddy, the Francis Crick Institute.

  • Sassone-Corsi, Paolo
  • Books

About this work


Our daily routines and physiological functions-and those of virtually all living organisms-are synchronized with the Earth's rotation about its axis. These include sleep patterns, hormone secretion, blood pressure, body temperature, and feeding behavior. Oscillations in these processes, or circadian rhythms, are controlled by molecular feedback loops that integrate with environmental and metabolic stimuli. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines the molecular and cellular details of the oscillatory machinery and how they control aspects of our physiology. Contributors discuss the cell-autonomous generation of circadian time and how those mechanisms interact with circuit-level mechanisms in the suprachiasmatic nucleus. Links between circadian and redox systems, as well as the relationship between circadian oscillations and pathogenic infections, are also covered. In addition, the authors examine circadian rhythms in other species (e.g., plants and Drosophila) and how they enable the organisms to adapt to their environments. This volume will therefore serve as a valuable reference for not only neurobiologists and cell and molecular biologists, but all who wish to understand the clocks and rhythms of life.


Cold Spring Harbor, New York : Cold Spring Harbor Laboratory Press, [2018]

Physical description

vii, 223 pages : illustrations (some colour) ; 27 cm.

Bibliographic information

Includes bibliographical references and index.


Machine generated contents note: Cellular Timekeeping: It's Redox o'clock / Akhilesh B. Reddy -- Regulating the Suprachiasmatic Nucleus (SCN) Circadian Clockwork: Interplay between Cell-Autonomous and Circuit-Level Mechanisms / Michael H. Hastings -- Membrane Currents, Gene Expression, and Circadian Clocks / Christopher S. Colwell -- Molecular Mechanisms of Sleep Homeostasis in Flies and Mammals / Amita Sehgal -- The Plant Circadian Clock: From a Simple Timekeeper to a Complex Developmental Manager / Steve A. Kay -- Design Principles of Phosphorylation-Dependent Timekeeping in Eukaryotic Circadian Clocks / Hiroki R. Ueda -- Systems Chronobiology: Global Analysis of Gene Regulation in a 24-Hour Periodic World / Felix Naef -- Circadian Posttranscriptional Regulatory Mechanisms in Mammals / Carta B. Green -- Coordination between Differentially Regulated Circadian Clocks Generates Rhythmic Behavior / Michael W. Young -- Interplay between Microbes and the Circadian Clock / Paolo Sassone-Corsi -- A 50-Year Personal Journey: Location, Gene Expression, and Circadian Rhythms / Michael Rosbash.


  • English

Where to find it

  • Location

    Medical Collection QT167 2018C57


    Open shelves

Permanent link



  • 9781621821243
  • 1621821242