Hydrophobia : M. Pasteur and his methods : a critical analysis / by Thomas M. Dolan.

Thomas M. Dolan

Date:: 1886

Credit: Hydrophobia : M. Pasteur and his methods : a critical analysis / by Thomas M. Dolan. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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phalon of rabid subjects are virzdent. The medulla oblongata is always virulent. The spinal cord is also virulent in parts, and frequently throughout its entire length ; the encephalon is virulent, some- times only in certain parts, sometimes in its en- tirety, M. Pasteur deserves the credit for herein stating some new facts and working on new lines, though this statement has to be very much modified by another, viz., that the cord may have virulent properties whilst the medulla is unaffected, the difference being explained by the mode of inocu- lation, intra-venous injections causing medullary hydrophobia owing to the localisation of the poison in that part. In other words, there is fixation of the poison in the spinal cord. Here we are placed in the presence of a seeming contradiction, on the fixation of the poison in the spinal cord in one case, when intra-venous injection is used, producing medullary hydrophobia, whilst in a subsequent communication M, Pasteur assures us that the form of hydrophobia, and consequent fixa- tion in cord, or brain, depends more upon the quantity of the virus introduced. As we are here speaking of the fixation of the virus in the nervous system, it seems appropriate to give in full the conclusions of M. Dubou6, so as to compare them with Pasteur's theories. M. Duboue* arrives at one primary con- * De la Physiologie Pathologique et du Traitement Rationnel Je la Rage, par le Docteur Dubou^ (de Pau). Paris : Adrien Delahaye.

Hydrophobia : M. Pasteur and his methods : a critical analysis / by Thomas M. Dolan.

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