The pathology of the cranial nerves in tabes dorsalis / by Tom A. Williams.

  • Williams, Tom A. (Tom Alfred), 1870-
Date:
1910
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Licence: In copyright

Credit: The pathology of the cranial nerves in tabes dorsalis / by Tom A. Williams. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    neighboring meninges are much altered, even obliterated, endo- neuritis appearing, and that the inflammation is still present outside Fig. 2 Fig. 3 Fig. 4 Fig. 5 Fig. 2.—Transverse section (diiigrammatic) of the region shown in Fig. 1, the section being made through the cavernous sinus proximal to the mark X. It shows the oculomotor nerve, A, lying in its meningeal gutter in the root of the sinus. There is at this situation no visible arachnoiditis. B, situation of the fourth and sLxth cranial nerves; C, situation of the ophthalmic branch of the fifth nerve; D, internal carotid artery. Fig. 3.—The tliird nerve. A, is now completely surrounded by its canal of dura and arachnoid matter, which are not yet adherent. The trabeculai of endoneuritis are visible; other structures are as in Fig. 2. Fig. 4.—The inflamed arachnoid is shown adhering to the third nerve at one place. The endoneuritis is still more evident than in Fig. 3. Note the increase in volume of the nerve. Fig. 5.—The third nerve is shown transversed and disassociated by thick trabecula; of connective tissue. Note the enormous increase in diameter of the nerve as against Figs. 2, 3, and 4, which are dra^vn to the same scale. The increased volume is due to the fibrinoplastic e.xudate and the round-cell infiltration within the sheath. the sheath of the nerve, with the characteristic lymphocytes and, above all, plasma cells with the perinuclear halo. Thus it is clear that we have over both third nerves the cicatrix of an old inflam- matory focus of localized interstitial neuritis. The Nerve Fibers (Figs. 8 and 9). The Weigert method shows the paleness of some of the nerve fibers among the dark violet of those remaining normal. Osmic acid shows the dwarfed and pale