Experimental researches on the physiological and therapeutic action of phosphate of lime / by L. Dusart.

  • Dusart, Lucien O.
Date:
1885
Catalogue details

Licence: Public Domain Mark

Credit: Experimental researches on the physiological and therapeutic action of phosphate of lime / by L. Dusart. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    extremity of the member. This increase of weight, already sensible in the animals submitted to the ordinary regimen, is still more marked in those to whom the lacto-phosphate is administered. In fine, we have always observed the production of a callus relatively more voluminous in these animals and in this we agree with several practitioners who had noticed the same fact in patients affected with fracture and taking the lacto-phosphate of lime in doses of 4 to 6 grammes a day. In presence of these results we have perceived the great interest which there is to establish scientifically, in the cases of fracture in man, how much the time necessary for consolidation would be lessened. To solve such a problem so simple in appearance, we have seen that it will at first be necessary to es- tablish by a rigorous statistic the normal duration of fractures in individuals comprised in definite limits of age, taking into account, for each series of cases, the seat of the fracture and the physiological state of the patient. We have shrunk from the material diffi- culties of the problem, but we do not the less persist in thinking that the preceding experiments incontest- ably establish the fact of the rapid assimilation of the phosphate of lime, and that there is in the greater number of cases advantage for the practitioner to admit the use of the lacto-phosphate of lime, as much as an adjuvant to osseous reproduction, as a stimulant of nutrition. Bearing in mind the observations and facts, which we have just related, and which all owe their value to direct experiments, do they warrant the assertion that phosphate of lime possesses the virtue we as- 4