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Prader Willi & Angelman's syndromes - probes

Wessex Reg. Genetics Centre
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Credit: Prader Willi & Angelman's syndromes - probes. Credit: Wessex Reg. Genetics Centre. Attribution 4.0 International (CC BY 4.0)

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Human chromosome highlighted by fluorescent probes that bind to specific sequences of DNA. This FISH (fluorescence in situ hybridisation) study uses a probe (red) from the Prader Willi and Angelman's syndromes critical regions (PWASCR) and a centromere specific probe for chromosome 15 (green) to show that this 15q11.>q13 duplication does not include the PWASCR. Image by Dr John Crolla


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